70 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28111140	24	Discovery of core-structurally novel PTP1B inhibitors with specific selectivity containing oxindole-fused spirotetrahydrofurochroman by one-pot reaction.	East China Normal University
28202316	3	An epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla.	University of Arizona
27123900	17	Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.	Qilu University of Technology
26774579	140	Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.	Shanghai Institute of Materia Medica
26481657	20	Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic.	Qilu University of Technology
26191366	66	Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.	Indiana University School of Medicine
25162754	2	Structure-based optimization of a peptidyl inhibitor against calcineurin-nuclear factor of activated T cell (NFAT) interaction.	The Ohio State University
26100442	17	Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design.	Qilu University of Technology
25907364	29	A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.	Indiana University
25872983	57	Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors.	Chinese Academy of Sciences
25124112	54	Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitors.	Liaoning Normal University
25003231	59	Therapeutic potential of targeting the oncogenic SHP2 phosphatase.	Indiana University School of Medicine
24906513	21	4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B.	Chinese Academy of Sciences
25497963	19	Bioactive constituents from the green alga Caulerpa racemosa.	Nanchang University
24090912	54	Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy.	Chinese Academy of Sciences
23957426	14	Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).	Case Western Reserve University
23942421	43	The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors.	Chinese Academy of Sciences
23713581	75	A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.	Indiana University School of Medicine
23305444	171	Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.	Indiana University School of Medicine
23122522	25	Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors.	East China University of Science and Technology
22444684	9	Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties.	Chinese Academy of Sciences
17728130	36	2-O-carboxymethylpyrogallol derivatives as PTP1B inhibitors with antihyperglycemic activity.	Inha University
17368023	24	Methylenedisalicylic acid derivatives: new PTP1B inhibitors that confer resistance to diet-induced obesity.	Inha University
11741477	37	Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.	University of Waterloo
22318165	85	Exploration ofa-aminophosphonate N-derivatives as novel, potent and selective inhibitors of protein tyrosine phosphatases.	Shanxi University
21745700	20	Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: novel construction of PTP1B inhibitors on a sugar scaffold.	East China University of Science and Technology
21680062	77	Synthesis and biological evaluation of (±)-3-(2-(2-fluorobenzyloxy) naphthalen-6-yl)-2-aminopropanoic acid derivatives as novel PTP1B inhibitors.	Yanbian University
20850970	27	Novel thiazolidinedione derivatives with anti-obesity effects: dual action as PTP1B inhibitors and PPAR-¿ activators.	Inha University
21669525	18	Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.	Indiana University
21665482	62	Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.	East China University of Science and Technology
21251827	60	A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides.	East China University of Science and Technology
21190368	60	Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.	Sanford-Burnham Medical Research Institute
21193311	22	Shp2 protein tyrosine phosphatase inhibitor activity of estramustine phosphate and its triterpenoid analogs.	H. Lee Moffitt Cancer Center and Research Institute
20363629	49	Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B.	Chinese Academy of Sciences
20170098	21	Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).	Indiana University School of Medicine
19846303	59	Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.	East China Normal University
19810703	102	Knowledge-based characterization of similarity relationships in the human protein-tyrosine phosphatase family for rational inhibitor design.	University of Miami
19783142	27	Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects.	Inha University
18722777	37	Derivatives of 1,4-bis(3-hydroxycarbonyl-4-hydroxyl)styrylbenzene as PTP1B inhibitors with hypoglycemic activity.	Inha University
18707891	152	Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.	Chinese Academy of Sciences
17692525	33	Mono- and disalicylic acid derivatives: PTP1B inhibitors as potential anti-obesity drugs.	Inha University
15743195	29	Design and biological evaluation of linear and cyclic phosphopeptide ligands of the N-terminal SH2 domain of protein tyrosine phosphatase SHP-1.	Friedrich-Schiller-University
12372498	23	alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship.	The Ohio State University
32787087	215	Highly Potent and Selective	Purdue University
32273218	21	Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.	Jiangnan University
30457860	5	Small Molecule Inhibitor that Stabilizes the Autoinhibited Conformation of the Oncogenic Tyrosine Phosphatase SHP2.	Emory University School of Medicine
31532203	24	Cinerols, Nitrogenous Meroterpenoids from the Marine Sponge	Shanghai Jiao Tong University
30711829	54	Toward a treatment of diabesity: In vitro and in vivo evaluation of uncharged bromophenol derivatives as a new series of PTP1B inhibitors.	Chinese Academy of Sciences
10464006	22	PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.	Wyeth-Ayerst Research
31095389	29	Diketopiperazine-Type Alkaloids from a Deep-Sea-Derived Aspergillus puniceus Fungus and Their Effects on Liver X Receptor ?.	Chinese Academy of Sciences
30525586	14	Celastrol Promotes Weight Loss in Diet-Induced Obesity by Inhibiting the Protein Tyrosine Phosphatases PTP1B and TCPTP in the Hypothalamus.	Helmholtz Zentrum M�Nchen
30978561	50	Synthesis and biological evaluation of tryptophan-derived rhodanine derivatives as PTP1B inhibitors and anti-bacterial agents.	Yanbian University College of Pharmacy
30910462	53	Discovery of 1,3-diphenyl-1H-pyrazole derivatives containing rhodanine-3-alkanoic acid groups as potential PTP1B inhibitors.	Yanbian University
25505942	8	Diversity-Oriented Synthesis for Novel, Selective and Drug-like Inhibitors for a Phosphatase from Mycobacterium Tuberculosis.	Indiana University School of Medicine
29100798	21	Benzo[c][1,2,5]thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.	Jiangnan University
29289892	32	Discovery of novel high potent and cellular active ADC type PTP1B inhibitors with selectivity over TC-PTP via modification interacting with C site.	Qilu University of Technology
29155585	9	Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.	Chinese Academy of Sciences
22380772	34	Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II.	Ataturk University
25352216	105	A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery.	University of California San Diego