The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28253618 |
104 |
Discovery of Benzenesulfonamides with Potent Human Carbonic Anhydrase Inhibitory and Effective Anticonvulsant Action: Design, Synthesis, and Pharmacological Assessment. |
University of Delhi |
| 28237553 |
76 |
Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds. |
Saint Petersburg State University |
| 28109946 |
84 |
Novel indolin-2-one-based sulfonamides as carbonic anhydrase inhibitors: Synthesis, in vitro biological evaluation against carbonic anhydrases isoforms I, II, IV and VII and molecular docking studies. |
Kafrelsheikh University |
| 28075587 |
102 |
Design and Synthesis of Novel Nonsteroidal Anti-Inflammatory Drugs and Carbonic Anhydrase Inhibitors Hybrids (NSAIDs-CAIs) for the Treatment of Rheumatoid Arthritis. |
University of Florence |
| 28111158 |
100 |
Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties. |
Abant Izzet Baysal University |
| 27919611 |
60 |
Discovery of 4-sulfamoyl-phenyl-ß-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors. |
National Institute of Pharmaceutical Education and Research (NIPER) |
| 27876475 |
68 |
Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII. |
Dumlupinar University |
| 27172398 |
20 |
An Unusual Natural Product Primary Sulfonamide: Synthesis, Carbonic Anhydrase Inhibition, and Protein X-ray Structures of Psammaplin C. |
Griffith University |
| 27298005 |
92 |
Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII. |
Dumlupinar University |
| 26805033 |
426 |
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII. |
Uppsala University |
| 26498394 |
105 |
Inhibition of mammalian carbonic anhydrase isoforms I-XIV with a series of phenolic acid esters. |
Universit£ |
| 26498393 |
116 |
New natural product carbonic anhydrase inhibitors incorporating phenol moieties. |
Aristotle University of Thessaloniki |
| 26347950 |
32 |
Phosphate Chemical Probes Designed for Location Specific Inhibition of Intracellular Carbonic Anhydrases. |
Griffith University |
| 26276436 |
45 |
Carbonic anhydrase inhibitors: Design, synthesis and structural characterization of new heteroaryl-N-carbonylbenzenesulfonamides targeting druggable human carbonic anhydrase isoforms. |
Universit£ |
| 26160114 |
101 |
Probing the 'bipolar' nature of the carbonic anhydrase active site: aromatic sulfonamides containing 1,3-oxazol-5-yl moiety as picomolar inhibitors of cytosolic CA I and CA II isoforms. |
Saint Petersburg State University |
| 25766630 |
100 |
A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects. |
Universit£ |
| 25468040 |
77 |
Inhibition studies of new ureido-substituted sulfonamides incorporating a GABA moiety against human carbonic anhydrase isoforms I-XIV. |
TBA |
| 25358084 |
143 |
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX. |
Vilnius University |
| 24689792 |
54 |
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes. |
Griffith University |
| 23394791 |
177 |
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII. |
Vilnius University Institute of Biotechnology |
| 23266178 |
115 |
Inhibition pattern of sulfamide-related compounds in binding to carbonic anhydrase isoforms I, II, VII, XII and XIV. |
National University of La Plata |
| 23010455 |
108 |
Synthesis of C-cinnamoyl glycosides and their inhibitory activity against mammalian carbonic anhydrases. |
Universidad Nacional De La Plata |
| 22892213 |
168 |
Natural product coumarins that inhibit human carbonic anhydrases. |
Griffith University |
| 22668600 |
200 |
Mono-/dihydroxybenzoic acid esters and phenol pyridinium derivatives as inhibitors of the mammalian carbonic anhydrase isoforms I, II, VII, IX, XII and XIV. |
Universit£ |
| 23067387 |
105 |
Tricyclic sulfonamides incorporating benzothiopyrano[4,3-c]pyrazole and pyridothiopyrano[4,3-c]pyrazole effectively inhibita- andß-carbonic anhydrase: X-ray crystallography and solution investigations on 15 isoforms. |
Universit£ |
| 22443141 |
115 |
Synthesis, structure-activity relationship studies, and X-ray crystallographic analysis of arylsulfonamides as potent carbonic anhydrase inhibitors. |
Universit£ |
| 22487176 |
109 |
Flavones and structurally related 4-chromenones inhibit carbonic anhydrases by a different mechanism of action compared to coumarins. |
Universit£ |
| 22440859 |
176 |
Design of [(2-pyrimidinylthio)acetyl]benzenesulfonamides as inhibitors of human carbonic anhydrases. |
Vilnius University |
| 20674354 |
79 |
Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV. |
Universit£ |
| 20605094 |
91 |
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. |
University of Florida |
| 20472429 |
80 |
Carbonic anhydrase inhibitors: crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 20185318 |
132 |
Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids. |
Universit£ |
| 19911821 |
273 |
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. |
Universita Degli Studi Di Firenze |
| 20028100 |
78 |
The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. |
Universit£ |
| 18406497 |
66 |
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents: structure-activity relationship and pharmacological evaluation. |
University of Namur |
| 19269822 |
75 |
Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions. |
Universit£ |
| 19186056 |
60 |
A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases. |
Universit£ |
| 18359629 |
84 |
Carbonic anhydrase inhibitors: the X-ray crystal structure of ethoxzolamide complexed to human isoform II reveals the importance of thr200 and gln92 for obtaining tight-binding inhibitors. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 17475500 |
130 |
Carbonic anhydrases as targets for medicinal chemistry. |
Universit£ |
| 17376683 |
63 |
Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 17314045 |
11 |
Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I. |
Universit£ |
| 16621537 |
19 |
Carbonic anhydrase inhibitors: inhibition of the cytosolic human isozyme VII with anions. |
Universit£ |
| 15686895 |
112 |
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides. |
Universit£ |
| 22365761 |
144 |
New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II. |
Universit£ |
| 22277279 |
9 |
Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors. |
Istituto Di Biostrutture E Bioimmagini-Cnr |
| 21821413 |
65 |
Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases. |
Ecole Nationale Sup£Rieure De Chimie De Montpellier |
| 21515057 |
153 |
Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies. |
Universit£ |
| 21620713 |
25 |
Conformational variability of different sulfonamide inhibitors with thienyl-acetamido moieties attributes to differential binding in the active site of cytosolic human carbonic anhydrase isoforms. |
University of Florida |
| 19435663 |
63 |
Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors. |
Istanbul University |
| 21506569 |
96 |
Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV. |
The Hebrew University of Jerusalem |
| 21395315 |
4 |
Structural basis for the interaction between carbonic anhydrase and 1,2,3,4-tetrahydroisoquinolin-2-ylsulfonamides. |
Academy of Sciences of The Czech Republic |
| 20926301 |
77 |
Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII. |
Institute of Biotechnology |
| 20889345 |
94 |
4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII. |
Vilnius University |
| 20590092 |
273 |
Polyamines inhibit carbonic anhydrases by anchoring to the zinc-coordinated water molecule. |
Universita Degli Studi Di Firenze |
| 19527930 |
53 |
The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms. |
University of Tampere and Tampere University Hospital |
| 32435377 |
30 |
Glycomimetic Based Approach toward Selective Carbonic Anhydrase Inhibitors. |
Universit£ |
| 32463228 |
151 |
Azidothymidine "Clicked" into 1,2,3-Triazoles: First Report on Carbonic Anhydrase-Telomerase Dual-Hybrid Inhibitors. |
Universit£ |
| 32435417 |
137 |
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms. |
Universit£ |
| 27305384 |
172 |
1,2-Benzisothiazole Derivatives Bearing 4-, 5-, or 6-Alkyl/arylcarboxamide Moieties Inhibit Carbonic Anhydrase Isoform IX (CAIX) and Cell Proliferation under Hypoxic Conditions. |
Universit£ |
| 32364386 |
184 |
Phenyl(thio)phosphon(amid)ate Benzenesulfonamides as Potent and Selective Inhibitors of Human Carbonic Anhydrases II and VII Counteract Allodynia in a Mouse Model of Oxaliplatin-Induced Neuropathy. |
University of Florence |
| 32031797 |
96 |
Discovery of Potent Dual-Tailed Benzenesulfonamide Inhibitors of Human Carbonic Anhydrases Implicated in Glaucoma and in Vivo Profiling of Their Intraocular Pressure-Lowering Action. |
University of Wollongong |
| 31794211 |
138 |
"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. |
University of Florence |
| 31693947 |
44 |
Direct and straightforward access to substituted alkyl selenols as novel carbonic anhydrase inhibitors. |
University of Florence |
| 31419777 |
68 |
Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells. |
University of Florence |
| 31476557 |
164 |
From random to rational: A discovery approach to selective subnanomolar inhibitors of human carbonic anhydrase IV based on the Castagnoli-Cushman multicomponent reaction. |
Saint Petersburg State University |
| 31401537 |
45 |
Synthesis of novel tellurides bearing benzensulfonamide moiety as carbonic anhydrase inhibitors with antitumor activity. |
University of Florence |
| 31136893 |
176 |
Benzensulfonamides bearing spyrohydantoin moieties act as potent inhibitors of human carbonic anhydrases II and VII and show neuropathic pain attenuating effects. |
University of Florence |
| 30530195 |
112 |
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl)benzenesulfonamide moiety. |
Universit£ |
| 31740053 |
1887 |
Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. |
Vilnius University |
| 30553625 |
761 |
Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases. |
Kaunas University of Technology |
| 26795114 |
72 |
Sulfamide derivatives with selective carbonic anhydrase VII inhibitory action. |
National University of La Plata |
| 26678172 |
70 |
Inhibition of carbonic anhydrase isoforms I, II, IV, VII and XII with carboxylates and sulfonamides incorporating phthalimide/phthalic anhydride scaffolds. |
King Saud University |
| 24300919 |
55 |
Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies. |
Universit£ |
| 24287559 |
36 |
Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors. |
Universit£ |
| 24103430 |
78 |
Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties. |
Universit£ |
| 24103428 |
271 |
Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII. |
Vilnius University |
| 24090602 |
21 |
Structural study of interaction between brinzolamide and dorzolamide inhibition of human carbonic anhydrases. |
University of Florida |
| 23965175 |
105 |
Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety. |
Birla Institute of Technology |
| 23910989 |
60 |
Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII. |
Dumlup?Nar University |
| 23867389 |
57 |
Carbonic anhydrase inhibitors: Synthesis and inhibition of the cytosolic mammalian carbonic anhydrase isoforms I, II and VII with benzene sulfonamides incorporating 4,5,6,7-tetrachlorophthalimide moiety. |
Birla Institute of Technology |
| 30015076 |
84 |
Discovery of potent anti-convulsant carbonic anhydrase inhibitors: Design, synthesis, in vitro and in vivo appraisal. |
University of Delhi |
| 30344913 |
24 |
Famotidine, an Antiulcer Agent, Strongly Inhibits |
University of Florence |
| 29305297 |
480 |
Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors. |
Vilnius University |
| 30006175 |
644 |
Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases. |
Vilnius University |
| 29803994 |
56 |
Design, synthesis and X-ray crystallography of selenides bearing benzenesulfonamide moiety with neuropathic pain modulating effects. |
Universit£ |
| 29795760 |
90 |
Design, Synthesis, and X-ray of Selenides as New Class of Agents for Prevention of Diabetic Cerebrovascular Pathology. |
University of Florence |
| 29259736 |
70 |
Synthesis of Novel Selenides Bearing Benzenesulfonamide Moieties as Carbonic Anhydrase I, II, IV, VII, and IX Inhibitors. |
University of Florence |
| 29057059 |
82 |
Lucky Switcheroo: Dramatic Potency and Selectivity Improvement of Imidazoline Inhibitors of Human Carbonic Anhydrase VII. |
Saint Petersburg State University |
| 28277280 |
43 |
Bortezomib inhibits mammalian carbonic anhydrases. |
Universit£ |
| 28522267 |
72 |
Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors. |
Universit£ |
| 28400084 |
68 |
Synthesis and biological evaluation of novel aromatic and heterocyclic bis-sulfonamide Schiff bases as carbonic anhydrase I, II, VII and IX inhibitors. |
Adiyaman University |
| 28302505 |
120 |
Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. |
Universit£ |
| 29466001 |
208 |
Introduction of Intrinsic Kinetics of Protein-Ligand Interactions and Their Implications for Drug Design. |
Vilnius University |
| 28453941 |
114 |
Probing Molecular Interactions between Human Carbonic Anhydrases (hCAs) and a Novel Class of Benzenesulfonamides. |
Universit£ |
| 10945872 |
14 |
Pharmacological actions of a novel, high-affinity, and selective human dopamine D(3) receptor antagonist, SB-277011-A. |
Smithkline Beecham Pharmaceuticals |
| 7815325 |
65 |
Cloning and pharmacological characterization of human alpha-1 adrenergic receptors: sequence corrections and direct comparison with other species homologues. |
Duke University |
| 3130534 |
3 |
7-[3-(4-[2,3-Dimethylphenyl]piperazinyl)propoxy]-2(1H)-quinolinone (OPC-4392), a presynaptic dopamine autoreceptor agonist and postsynaptic D2 receptor antagonist. |
Tokushima Research Institute |
| 2664084 |
17 |
Detection of a novel serotonin receptor subtype (5-HT1E) in human brain: interaction with a GTP-binding protein. |
Albany Medical College |
| 2547939 |
11 |
Characterization of the striatal M2 muscarinic receptor mediating inhibition of cyclic AMP using selective antagonists: a comparison with the brainstem M2 receptor. |
Abbott Laboratories |
| 2537406 |
2 |
Pharmacological characterization of the M1 muscarinic receptors expressed in murine fibroblast B82 cells. |
University of Arizona |
| 19900813 |
12 |
Optimization of (4,4-difluoro-1,2,3,4-tetrahydro-5H-1-benzazepine-5-ylidene)acetamide derivatives as arginine vasopressin V2 receptor agonists and discussion of their binding modes. |
Astellas Pharma |
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