Search and Browse
Download
Enter Data
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35666 (BMC173130 Compound 1t | benzazepinelidene acetamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | KEGG PC cid PC sid UniChem Similars | Article PubMed | 9.70 | -45.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35669 (benzazepinelidene acetamide derivative, 1d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 13 | -44.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35669 (benzazepinelidene acetamide derivative, 1d) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 13 | -44.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35672 (benzazepinelidene acetamide derivative, 1g) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35671 (benzazepinelidene acetamide derivative, 1f) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 14 | -44.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35670 (benzazepinelidene acetamide derivative, 1e) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 16 | -44.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35671 (benzazepinelidene acetamide derivative, 1f) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 17 | -44.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35666 (BMC173130 Compound 1t | benzazepinelidene acetamid...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 28 | -42.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35670 (benzazepinelidene acetamide derivative, 1e) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 39 | -42.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35672 (benzazepinelidene acetamide derivative, 1g) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 43 | -41.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V2 receptor (Homo sapiens (Human)) | BDBM35668 (benzazepinelidene acetamide derivative, 1c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 78 | -40.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Vasopressin V1a receptor (Homo sapiens (Human)) | BDBM35668 (benzazepinelidene acetamide derivative, 1c) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 170 | -38.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 23 |
Astellas Pharma Inc. | Assay Description Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-... | Bioorg Med Chem 17: 8161-7 (2009) Article DOI: 10.1016/j.bmc.2009.10.038 BindingDB Entry DOI: 10.7270/Q28K77DW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
