Found 11 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 7
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 5.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA7 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 8.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA4 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 13
(Mus musculus (mouse)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 8.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CA13 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 12
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 1.29E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA12 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 6
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 1.81E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA6 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 9
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 2.21E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA9 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 14
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA14 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5B, mitochondrial
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 1.18E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA5B by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 1.42E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA2 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 1
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 2.41E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of cloned human CA1 by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 5A, mitochondrial
(Homo sapiens (Human)) | BDBM50027536
((phosphonoformate)Trisodium phosphonoformate | Ant...)Show InChI InChI=1S/CH3O5P/c2-1(3)7(4,5)6/h(H,2,3)(H2,4,5,6)/p-3 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| 4.17E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CA5A by CO2 hydration assay |
Bioorg Med Chem Lett 17: 2210-5 (2007)
Article DOI: 10.1016/j.bmcl.2007.01.113 BindingDB Entry DOI: 10.7270/Q21C1XP7 |
More data for this Ligand-Target Pair | |