The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28621538 |
63 |
Discovery of Highly Potent and Selective Small-Molecule Reversible Factor D Inhibitors Demonstrating Alternative Complement Pathway Inhibition in Vivo. |
Novartis Pharma |
28157311 |
11 |
Structure-Based Library Design and Fragment Screening for the Identification of Reversible Complement Factor D Protease Inhibitors. |
Novartis Institutes For Biomedical Research |
27914800 |
11 |
Discovery of a new isomannide-based peptidomimetic synthetized by Ugi multicomponent reaction as human tissue kallikrein 1 inhibitor. |
Universidade Federal Fluminense |
27155563 |
5 |
Isocoumarins, miraculous natural products blessed with diverse pharmacological activities. |
Quaid-I-Azam University |
26848109 |
8 |
The natural flavone fukugetin as a mixed-type inhibitor for human tissue kallikreins. |
Campus |
26393374 |
34 |
Improving the Selectivity of Engineered Protease Inhibitors: Optimizing the P2 Prime Residue Using a Versatile Cyclic Peptide Library. |
Queensland University of Technology |
25682203 |
13 |
Pyrido-imidazodiazepinones as a new class of reversible inhibitors of human kallikrein 7. |
University of Montpellier |
24900785 |
64 |
Isomannide-based peptidomimetics as inhibitors for human tissue kallikreins 5 and 7. |
Universidade Federal Do Abc |
24211642 |
49 |
Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins. |
Universit£ |
23849879 |
23 |
1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases. |
Universit£ |
22959247 |
20 |
Isomannide derivatives as new class of inhibitors for human kallikrein 7. |
Universidade Federal Do Tri£Ngulo Mineiro |
21903387 |
12 |
Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. |
Universidade Federal Do Tri£Ngulo Mineiro |
30691925 |
34 |
Kallikrein 5 inhibitors identified through structure based drug design in search for a treatment for Netherton Syndrome. |
Glaxosmithkline R&D |
31521475 |
205 |
Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors. |
Glaxosmithkline |
31005442 |
64 |
Structure guided drug design to develop kallikrein 5 inhibitors to treat Netherton syndrome. |
Glaxosmithkline R&D |
31855419 |
63 |
Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors. |
The University of Queensland |
30522951 |
32 |
Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors. |
Asubio Pharma |
30888159 |
18 |
Amino Acid Scanning at P5' within the Bowman-Birk Inhibitory Loop Reveals Specificity Trends for Diverse Serine Proteases. |
The University of Queensland |
30613336 |
32 |
Potent, Selective, and Cell-Penetrating Inhibitors of Kallikrein-Related Peptidase 4 Based on the Cyclic Peptide MCoTI-II. |
The University of Queensland |
30833107 |
18 |
3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7. |
Universidade Federal Fluminense |
29550094 |
28 |
Structure-based drug design of 1,3,6-trisubstituted 1,4-diazepan-7-ones as selective human kallikrein 7 inhibitors. |
Asubio Pharma |
30212625 |
107 |
Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity. |
German Cancer Research Center (Dkfz) |
29102227 |
19 |
Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors. |
Asubio Pharma |
30015488 |
44 |
Discovery, Synthesis, Pharmacological Profiling, and Biological Characterization of Brintonamides A-E, Novel Dual Protease and GPCR Modulators from a Marine Cyanobacterium. |
University of Florida |
29884582 |
42 |
Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones. |
Asubio Pharma |
28045523 |
35 |
Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold. |
The University of Queensland |
24158442 |
40 |
Transition state analogues of Plasmodium falciparum and human orotate phosphoribosyltransferases. |
Albert Einstein College of Medicine |
17028581 |
3 |
Inhibitors of Polo-like kinase reveal roles in spindle-pole maintenance. |
University of Cambridge |
10715152 |
151 |
5,6-Dihydropyran-2-ones possessing various sulfonyl functionalities: potent nonpeptidic inhibitors of HIV protease. |
Parke-Davis Pharmaceutical Research |