The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
11266171 |
4 |
RPR203494 a pyrimidine analogue of the p38 inhibitor RPR200765A with an improved in vitro potency. |
Aventis Pharma |
28280261 |
84 |
Non-kinase targets of protein kinase inhibitors. |
The University of Sydney |
22901390 |
44 |
Synthesis and biological activity of pyridopyridazin-6-one p38a MAP kinase inhibitors. Part 2. |
Merck Research Laboratories |
18039577 |
62 |
Imidazolyl benzimidazoles and imidazo[4,5-b]pyridines as potent p38alpha MAP kinase inhibitors with excellent in vivo antiinflammatory properties. |
Eli Lilly |
15177483 |
33 |
SAR of benzoylpyridines and benzophenones as p38alpha MAP kinase inhibitors with oral activity. |
Novartis Institutes For Biomedical Research |
20378346 |
25 |
Synthesis and biological activity of 2H-quinolizin-2-one based p38alpha MAP kinase inhibitors. |
Merck Research Laboratories |
16249085 |
26 |
Pyrazoloheteroaryls: novel p38alpha MAP kinase inhibiting scaffolds with oral activity. |
Novartis Institutes For Biomedical Research |
15177482 |
90 |
Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis. |
Novartis Institutes For Biomedical Research |
14698158 |
13 |
A novel Pd-catalyzed cyclization reaction of ureas for the synthesis of dihydroquinazolinone p38 kinase inhibitors. |
Novartis Institute For Biomedical Research |
12565927 |
24 |
Imidazopyrimidines, potent inhibitors of p38 MAP kinase. |
Johnson & Johnson Pharmaceutical Research and Development |
12540232 |
53 |
Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones. |
Merck Research Laboratories |
12127515 |
29 |
SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38MAP kinase inhibitors. |
Novartis Pharma |
32543856 |
3 |
Mining the PDB for Tractable Cases Where X-ray Crystallography Combined with Fragment Screens Can Be Used to Systematically Design Protein-Protein Inhibitors: Two Test Cases Illustrated by IL1?-IL1R and p38?-TAB1 Complexes. |
King'S College London |
10866395 |
33 |
SAR of 4-hydroxypiperidine and hydroxyalkyl substituted heterocycles as novel p38 map kinase inhibitors. |
Novartis Pharma |