58 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27123900	17	Discovery of novel, high potent, ABC type PTP1B inhibitors with TCPTP selectivity and cellular activity.	Qilu University Of Technology
26774579	140	Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.	Shanghai Institute Of Materia Medica
26481657	20	Novel, potent, selective and cellular active ABC type PTP1B inhibitors containing (methanesulfonyl-phenyl-amino)-acetic acid methyl ester phosphotyrosine mimetic.	Qilu University Of Technology
26191366	66	Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.	Indiana University School Of Medicine
26100442	17	Discovery of novel, potent, selective and cellular active ADC type PTP1B inhibitors via fragment-docking-oriented de novel design.	Qilu University Of Technology
25921264	21	Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.	Sanford-Burnham Medical Research Institute
25907364	29	A potent and selective inhibitor for the UBLCP1 proteasome phosphatase.	Indiana University
25124112	54	Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitors.	Liaoning Normal University
25497963	19	Bioactive constituents from the green alga Caulerpa racemosa.	Nanchang University
24090912	54	Design, synthesis, and biological evaluation of novel 2-ethyl-5-phenylthiazole-4-carboxamide derivatives as protein tyrosine phosphatase 1B inhibitors with improved cellular efficacy.	Chinese Academy Of Sciences
24083656	52	Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.	Yale University
24012179	30	Calix[4]arene methylenebisphosphonic acids as inhibitors of protein tyrosine phosphatase 1B.	National Academy Of Sciences Of Ukraine
23957426	14	Identification of cryptotanshinone as an inhibitor of oncogenic protein tyrosine phosphatase SHP2 (PTPN11).	Case Western Reserve University
23942421	43	The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors.	Chinese Academy Of Sciences
23305444	171	Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.	Indiana University School Of Medicine
23122522	25	Discovery of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B inhibitors.	East China University Of Science And Technology
21453996	20	Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches.	Universidad Aut£Noma Del Estado De Morelos
22444684	9	Bromophenols as inhibitors of protein tyrosine phosphatase 1B with antidiabetic properties.	Chinese Academy Of Sciences
21116447	65	Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.	Indiana University School Of Medicine
20153651	37	Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity.	Chinese Academy Of Sciences
17543532	46	5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases.	Universit£
21745700	20	Click to a focused library of benzyl 6-triazolo(hydroxy)benzoic glucosides: novel construction of PTP1B inhibitors on a sugar scaffold.	East China University Of Science And Technology
20850970	27	Novel thiazolidinedione derivatives with anti-obesity effects: dual action as PTP1B inhibitors and PPAR-¿ activators.	Inha University
21669525	18	Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening.	Indiana University
21665482	62	Facile fabrication of promising protein tyrosine phosphatase (PTP) inhibitor entities based on 'clicked' serine/threonine-monosaccharide hybrids.	East China University Of Science And Technology
21443195	9	Utilization of nitrophenylphosphates and oxime-based ligation for the development of nanomolar affinity inhibitors of the Yersinia pestis outer protein H (YopH) phosphatase.	National Cancer Institute-Frederick
21251827	60	A unique and rapid approach toward the efficient development of novel protein tyrosine phosphatase (PTP) inhibitors based on 'clicked' pseudo-glycopeptides.	East China University Of Science And Technology
21190368	60	Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.	Sanford-Burnham Medical Research Institute
20627471	54	Synthesis and evaluation of some novel dibenzo[b,d]furan carboxylic acids as potential anti-diabetic agents.	Glenmark Research Center
19889539	49	Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.	University Of California
19782562	10	Isolation of the protein tyrosine phosphatase 1B inhibitory metabolite from the marine-derived fungus Cosmospora sp. SF-5060.	Silla University
20170098	21	Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).	Indiana University School Of Medicine
19846303	59	Synthesis and biological evaluation of heterocyclic ring-substituted maslinic acid derivatives as novel inhibitors of protein tyrosine phosphatase 1B.	East China Normal University
19810703	102	Knowledge-based characterization of similarity relationships in the human protein-tyrosine phosphatase family for rational inhibitor design.	University Of Miami
19783142	27	Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects.	Inha University
19349096	81	Synthesis and evaluation of some novel isochroman carboxylic acid derivatives as potential anti-diabetic agents.	Glenmark Research Center
18707891	152	Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities.	Chinese Academy Of Sciences
18579388	18	Illudalic acid as a potential LAR inhibitor: synthesis, SAR, and preliminary studies on the mechanism of action.	Chinese Academy Of Sciences
17705360	76	Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.	Wyeth Research
16759857	59	Design and synthesis of potent, non-peptidic inhibitors of HPTPbeta.	Procter & Gamble Pharmaceuticals
16289879	34	PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives.	Korea Research Institute Of Chemical Technology
14611852	34	Identification of a novel class of orally active pyrimido[5,4-3][1,2,4]triazine-5,7-diamine-based hypoglycemic agents with protein tyrosine phosphatase inhibitory activity.	Roche Research Center
12951078	38	Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.	Abbott Laboratories
12877578	33	Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.	Abbott Laboratories
12852966	23	Formylchromone derivatives as a novel class of protein tyrosine phosphatase 1B inhibitors.	Inha University
12238924	145	Discovery and SAR of a novel selective and orally bioavailable nonpeptide classical competitive inhibitor class of protein-tyrosine phosphatase 1B.	Novo Nordisk
12190316	15	Divalent and trivalent alpha-ketocarboxylic acids as inhibitors of protein tyrosine phosphatases.	Brown University
12113814	60	Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents.	Korea Research Institute Of Chemical Technology
10753467	118	Novel benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties.	Wyeth-Ayerst Research
10464006	22	PTP1B inhibition and antihyperglycemic activity in the ob/ob mouse model of novel 11-arylbenzo[b]naphtho[2,3-d]furans and 11-arylbenzo[b]naphtho[2,3-d]thiophenes.	Wyeth-Ayerst Research
22380772	34	Secondary/tertiary benzenesulfonamides with inhibitory action against the cytosolic human carbonic anhydrase isoforms I and II.	Ataturk University
25352216	105	A Molecular Dynamics Investigation of Mycobacterium tuberculosis Prenyl Synthases: Conformational Flexibility and Implications for Computer-aided Drug Discovery.	University Of California San Diego
2971798	9	[3H]SCH 23390 labels both dopamine-1 and 5-hydroxytryptamine1c receptors in the choroid plexus.	University Of Pennsylvania