88 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
28182990	8	Design, synthesis and biological evaluation of novel non-peptide boronic acid derivatives as proteasome inhibitors.	China Pharmaceutical University
28027531	28	Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors.	Hangzhou Xixi Hospital
27889629	23	Terminal functionalized thiourea-containing dipeptides as multidrug-resistance reversers that target 20S proteasome and cell proliferation.	Guangxi Normal University
28435528	24	Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit.	Kezar Life Sciences
27765408	16	Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors.	Hangzhou Xixi Hospital
27318981	11	Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening.	University of Naples Federico Ii
27311892	1	Cupriphilic compounds to aid in proteasome inhibition.	University of South Florida
27112450	52	Substituted quinolines as noncovalent proteasome inhibitors.	Michigan State University
27158142	36	Development of novel proteasome inhibitors based on phthalazinone scaffold.	Peking University Health Science Center
27117691	85	3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies.	Nanjing Forestry University
26965867	10	Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed fromaa- andaß-amino acids.	China Pharmaceutical University
26231162	2	Structure-activity relationship study of syringolin A as a potential anticancer agent.	Hokkaido University
26296913	16	Substrate-guided optimization of the syringolins yields potent proteasome inhibitors with activity against leukemia cell lines.	Brown University
25769015	2	Cystargolides, 20S Proteasome Inhibitors Isolated from Kitasatospora cystarginea.	University of Prince Edward Island
26005024	10	Discovery of novel non-covalent inhibitors selective to theß5-subunit of the human 20S proteasome.	Chinese Academy of Medical Sciences and Peking Union Medical College
24946214	24	Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors.	Universit£
24561716	18	Identification of a new series of amides as non-covalent proteasome inhibitors.	Universit£
24524217	65	Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates.	Hokkaido University
24321833	95	A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor.	Institute of Bio-Science and Technology
24269479	11	(S)-4-Trimethylsilyl-3-butyn-2-ol as an auxiliary for stereocontrolled synthesis of salinosporamide analogs with modifications at positions C2 and C5.	The Pennsylvania State University
23639651	20	Development of peptidomimetic boronates as proteasome inhibitors.	Universit£
23547706	2	Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors.	Moffitt Cancer Center
23547757	42	Potent proteasome inhibitors derived from the unnatural cis-cyclopropane isomer of Belactosin A: synthesis, biological activity, and mode of action.	Hokkaido University
23540790	57	Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome.	University Paris 6
23294826	1	Further characterization of a putative serine protease contributing to the¿-secretase cleavage ofß-amyloid precursor protein.	University of Montpellier
23320547	69	Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites.	Leiden Institute of Chemistry and Netherlands Proteomics Centre
22978849	13	Molecular mechanisms of acquired proteasome inhibitor resistance.	University of California San Diego
16603348	12	P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors.	University of Ferrara
20131905	24	Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites.	Gorlaeus Laboratories
17125278	1	Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells.	Wayne State University
16686537	165	Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and cellular properties of potent, selective proteasome inhibitors.	Celera
32189500	56	LMP2 Inhibitors as a Potential Treatment for Alzheimer's Disease.	University of Kentucky
27563406	128	Discovery of Fluoromethylketone-Based Peptidomimetics as Covalent ATG4B (Autophagin-1) Inhibitors.	Roche Pharma Research and Early Development
27438186	172	Structure-Based Design of ?5c Selective Inhibitors of Human Constitutive Proteasomes.	Leiden Institute of Chemistry
30776692	41	Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system.	Institute of Agricultural and Food Biotechnology
30639896	42	Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles.	Hangzhou Institute of Innovative Medicine
31560200	30	Selective Phenylimidazole-Based Inhibitors of the	Weill Cornell Medicine
30611983	48	Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors.	Zhejiang University
30380863	196	Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S,3 R)- N-(( S)-3-(Cyclopent-1-en-1-yl)-1-(( R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-(( S)-2-(2-morpholinoacetamido)propanamido)propenamide).	Kezar Life Sciences
31732281	21	Identification of neomacrophorins isolated from Trichoderma sp. 1212-03 as proteasome inhibitors.	Iwate University
31521028	67	Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases.	Hangzhou Xixi Hospital
31312413	75	Synthesis and Biological Activity of Peptide ?-Ketoamide Derivatives as Proteasome Inhibitors.	University of Ferrara
31383629	29	Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors.	Nanjing Forestry University
30964987	13	Development of Novel Epoxyketone-Based Proteasome Inhibitors as a Strategy To Overcome Cancer Resistance to Carfilzomib and Bortezomib.	University of Kentucky
30587447	3	Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators.	Purdue University
30452262	14	Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity.	University of Gdansk
30265557	31	Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors.	Zhejiang University
30657666	263	Structure-Based Design of Inhibitors Selective for Human Proteasome ?2c or ?2i Subunits.	Leiden Institute of Chemistry and Netherlands Proteomics Centre
31288128	6	Boron in drug design: Recent advances in the development of new therapeutic agents.	S£O Paulo State University
31177777	54	Improvement of Asparagine Ethylenediamines as Anti-malarial	Weill Cornell Medicine
31801019	5	Novel Cell-Penetrating Peptide Conjugated Proteasome Inhibitors: Anticancer and Antifungal Investigations.	University of Auckland
30391816	43	Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors.	Zhejiang University
30581047	11	Tripeptide analogues of MG132 as protease inhibitors.	University of Adelaide
30455150	10	Tetradehydrohalicyclamine B, a new proteasome inhibitor from the marine sponge Acanthostrongylophora ingens.	Kumamoto University
17249727	8	Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.	Intermed Discovery Gmbh (Imd)
15780623	39	Structure-based design of derivatives of tyropeptin A as the potent and selective inhibitors of mammalian 20S proteasome.	Numazu Bio-Medical Research Institute
7608891	7	Potent inhibitors of proteasome.	Cephalon
11992770	19	Structure-based optimisation of 2-aminobenzylstatine derivatives: potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome.	Novartis Pharma
30165344	63	Design, synthesis, and evaluation of cystargolide-based ?-lactones as potent proteasome inhibitors.	New Mexico Institute of Mining and Technology
29339252	124	Structure-based design of human immuno- and constitutive proteasomes inhibitors.	Universit£
29934218	32	Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies.	Nanjing Forestry University
29886021	6	Synthesis and biological evaluation of curcumin derivatives modified with ?-amino boronic acid as proteasome inhibitors.	Peking University
29652143	22	Reviewing Hit Discovery Literature for Difficult Targets: Glutathione Transferase Omega-1 as an Example.	Monash University
29407987	115	Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death.	Nagahama Institute of Bio-Science and Technology
30365892	22	Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor.	Heinrich Heine University D£Sseldorf
29782167	48	Potent and Highly Selective Inhibitors of the Proteasome Trypsin-like Site by Incorporation of Basic Side Chain Containing Amino Acid Derived Sulfonyl Fluorides.	University of Glasgow
29773504	13	Discovery of novel 20S proteasome inhibitors by rational topology-based scaffold hopping of bortezomib.	Fudan University
28445065	3	Neomacrophorin X, a [4.4.3]Propellane-Type Meroterpenoid from Trichoderma sp. 1212-03.	Hirosaki University
28634039	6	Synthesis and biological activity of peptide proline-boronic acids as proteasome inhibitors.	Peking University
28441582	19	Synthesis and antiproteasomal activity of novel O-benzyl salicylamide-based inhibitors built from leucine and phenylalanine.	Palack£
27769033	46	Urea-containing peptide boronic acids as potent proteasome inhibitors.	Peking University
28696697	3	Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity.	University of California
28236510	55	A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids.	Baylor University
21774748	30	Synthesis and structure-activity relationship of novel conformationally restricted analogues of serotonin as 5-HT6 receptor ligands.	Suven Life Sciences
2250662	140	Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells.	Glaxo Group Research