The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28182990 |
8 |
Design, synthesis and biological evaluation of novel non-peptide boronic acid derivatives as proteasome inhibitors. |
China Pharmaceutical University |
28027531 |
28 |
Exploration of novel piperazine or piperidine constructed non-covalent peptidyl derivatives as proteasome inhibitors. |
Hangzhou Xixi Hospital |
27889629 |
23 |
Terminal functionalized thiourea-containing dipeptides as multidrug-resistance reversers that target 20S proteasome and cell proliferation. |
Guangxi Normal University |
28435528 |
24 |
Discovery of Highly Selective Inhibitors of the Immunoproteasome Low Molecular Mass Polypeptide 2 (LMP2) Subunit. |
Kezar Life Sciences |
27765408 |
16 |
Design, synthesis and biological evaluation of novel non-covalent piperidine-containing peptidyl proteasome inhibitors. |
Hangzhou Xixi Hospital |
27318981 |
11 |
Identification of noncovalent proteasome inhibitors with high selectivity for chymotrypsin-like activity by a multistep structure-based virtual screening. |
University of Naples Federico Ii |
27311892 |
1 |
Cupriphilic compounds to aid in proteasome inhibition. |
University of South Florida |
27112450 |
52 |
Substituted quinolines as noncovalent proteasome inhibitors. |
Michigan State University |
27158142 |
36 |
Development of novel proteasome inhibitors based on phthalazinone scaffold. |
Peking University Health Science Center |
27117691 |
85 |
3D-QSAR-aided design, synthesis, in vitro and in vivo evaluation of dipeptidyl boronic acid proteasome inhibitors and mechanism studies. |
Nanjing Forestry University |
26965867 |
10 |
Design, synthesis and docking studies of novel dipeptidyl boronic acid proteasome inhibitors constructed fromaa- andaß-amino acids. |
China Pharmaceutical University |
26231162 |
2 |
Structure-activity relationship study of syringolin A as a potential anticancer agent. |
Hokkaido University |
26296913 |
16 |
Substrate-guided optimization of the syringolins yields potent proteasome inhibitors with activity against leukemia cell lines. |
Brown University |
25769015 |
2 |
Cystargolides, 20S Proteasome Inhibitors Isolated from Kitasatospora cystarginea. |
University of Prince Edward Island |
26005024 |
10 |
Discovery of novel non-covalent inhibitors selective to theß5-subunit of the human 20S proteasome. |
Chinese Academy of Medical Sciences and Peking Union Medical College |
24946214 |
24 |
Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors. |
Universit£ |
24561716 |
18 |
Identification of a new series of amides as non-covalent proteasome inhibitors. |
Universit£ |
24524217 |
65 |
Structurally novel highly potent proteasome inhibitors created by the structure-based hybridization of nonpeptidic belactosin derivatives and peptide boronates. |
Hokkaido University |
24321833 |
95 |
A novel tamoxifen derivative, ridaifen-F, is a nonpeptidic small-molecule proteasome inhibitor. |
Institute of Bio-Science and Technology |
24269479 |
11 |
(S)-4-Trimethylsilyl-3-butyn-2-ol as an auxiliary for stereocontrolled synthesis of salinosporamide analogs with modifications at positions C2 and C5. |
The Pennsylvania State University |
23639651 |
20 |
Development of peptidomimetic boronates as proteasome inhibitors. |
Universit£ |
23547706 |
2 |
Oxadiazole-isopropylamides as potent and noncovalent proteasome inhibitors. |
Moffitt Cancer Center |
23547757 |
42 |
Potent proteasome inhibitors derived from the unnatural cis-cyclopropane isomer of Belactosin A: synthesis, biological activity, and mode of action. |
Hokkaido University |
23540790 |
57 |
Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome. |
University Paris 6 |
23294826 |
1 |
Further characterization of a putative serine protease contributing to the¿-secretase cleavage ofß-amyloid precursor protein. |
University of Montpellier |
23320547 |
69 |
Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites. |
Leiden Institute of Chemistry and Netherlands Proteomics Centre |
22978849 |
13 |
Molecular mechanisms of acquired proteasome inhibitor resistance. |
University of California San Diego |
16603348 |
12 |
P3 and P4 position analysis of vinyl ester pseudopeptide proteasome inhibitors. |
University of Ferrara |
20131905 |
24 |
Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites. |
Gorlaeus Laboratories |
17125278 |
1 |
Novel Schiff base copper complexes of quinoline-2 carboxaldehyde as proteasome inhibitors in human prostate cancer cells. |
Wayne State University |
16686537 |
165 |
Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and cellular properties of potent, selective proteasome inhibitors. |
Celera |
32189500 |
56 |
LMP2 Inhibitors as a Potential Treatment for Alzheimer's Disease. |
University of Kentucky |
27438186 |
172 |
Structure-Based Design of ?5c Selective Inhibitors of Human Constitutive Proteasomes. |
Leiden Institute of Chemistry |
30776692 |
41 |
Another look at phenolic compounds in cancer therapy the effect of polyphenols on ubiquitin-proteasome system. |
Institute of Agricultural and Food Biotechnology |
30639896 |
42 |
Covalent docking modelling-based discovery of tripeptidyl epoxyketone proteasome inhibitors composed of aliphatic-heterocycles. |
Hangzhou Institute of Innovative Medicine |
31560200 |
30 |
Selective Phenylimidazole-Based Inhibitors of the |
Weill Cornell Medicine |
30611983 |
48 |
Exploration of novel macrocyclic dipeptide N-benzyl amides as proteasome inhibitors. |
Zhejiang University |
30380863 |
196 |
Required Immunoproteasome Subunit Inhibition Profile for Anti-Inflammatory Efficacy and Clinical Candidate KZR-616 ((2 S,3 R)- N-(( S)-3-(Cyclopent-1-en-1-yl)-1-(( R)-2-methyloxiran-2-yl)-1-oxopropan-2-yl)-3-hydroxy-3-(4-methoxyphenyl)-2-(( S)-2-(2-morpholinoacetamido)propanamido)propenamide). |
Kezar Life Sciences |
31732281 |
21 |
Identification of neomacrophorins isolated from Trichoderma sp. 1212-03 as proteasome inhibitors. |
Iwate University |
31521028 |
67 |
Immunoproteasome-selective inhibitors: An overview of recent developments as potential drugs for hematologic malignancies and autoimmune diseases. |
Hangzhou Xixi Hospital |
31312413 |
75 |
Synthesis and Biological Activity of Peptide ?-Ketoamide Derivatives as Proteasome Inhibitors. |
University of Ferrara |
31383629 |
29 |
Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors. |
Nanjing Forestry University |
30964987 |
13 |
Development of Novel Epoxyketone-Based Proteasome Inhibitors as a Strategy To Overcome Cancer Resistance to Carfilzomib and Bortezomib. |
University of Kentucky |
30452262 |
14 |
Proline- and Arginine-Rich Peptides as Flexible Allosteric Modulators of Human Proteasome Activity. |
University of Gdansk |
30265557 |
31 |
Development of Macrocyclic Peptides Containing Epoxyketone with Oral Availability as Proteasome Inhibitors. |
Zhejiang University |
30657666 |
263 |
Structure-Based Design of Inhibitors Selective for Human Proteasome ?2c or ?2i Subunits. |
Leiden Institute of Chemistry and Netherlands Proteomics Centre |
31288128 |
6 |
Boron in drug design: Recent advances in the development of new therapeutic agents. |
S£O Paulo State University |
31177777 |
54 |
Improvement of Asparagine Ethylenediamines as Anti-malarial |
Weill Cornell Medicine |
30391816 |
43 |
Design, synthesis, and biological evaluation of novel phenol ether derivatives as non-covalent proteasome inhibitors. |
Zhejiang University |
30581047 |
11 |
Tripeptide analogues of MG132 as protease inhibitors. |
University of Adelaide |
30455150 |
10 |
Tetradehydrohalicyclamine B, a new proteasome inhibitor from the marine sponge Acanthostrongylophora ingens. |
Kumamoto University |
30165344 |
63 |
Design, synthesis, and evaluation of cystargolide-based ?-lactones as potent proteasome inhibitors. |
New Mexico Institute of Mining and Technology |
29339252 |
124 |
Structure-based design of human immuno- and constitutive proteasomes inhibitors. |
Universit£ |
29934218 |
32 |
Design, synthesis, in vitro and in vivo evaluation, and structure-activity relationship (SAR) discussion of novel dipeptidyl boronic acid proteasome inhibitors as orally available anti-cancer agents for the treatment of multiple myeloma and mechanism studies. |
Nanjing Forestry University |
29886021 |
6 |
Synthesis and biological evaluation of curcumin derivatives modified with ?-amino boronic acid as proteasome inhibitors. |
Peking University |
29407987 |
115 |
Ridaifen-F conjugated with cell-penetrating peptides inhibits intracellular proteasome activities and induces drug-resistant cell death. |
Nagahama Institute of Bio-Science and Technology |
30365892 |
22 |
Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor. |
Heinrich Heine University D£Sseldorf |
29782167 |
48 |
Potent and Highly Selective Inhibitors of the Proteasome Trypsin-like Site by Incorporation of Basic Side Chain Containing Amino Acid Derived Sulfonyl Fluorides. |
University of Glasgow |
29773504 |
13 |
Discovery of novel 20S proteasome inhibitors by rational topology-based scaffold hopping of bortezomib. |
Fudan University |
28445065 |
3 |
Neomacrophorin X, a [4.4.3]Propellane-Type Meroterpenoid from Trichoderma sp. 1212-03. |
Hirosaki University |
28634039 |
6 |
Synthesis and biological activity of peptide proline-boronic acids as proteasome inhibitors. |
Peking University |
28441582 |
19 |
Synthesis and antiproteasomal activity of novel O-benzyl salicylamide-based inhibitors built from leucine and phenylalanine. |
Palack£ |
27769033 |
46 |
Urea-containing peptide boronic acids as potent proteasome inhibitors. |
Peking University |
28696697 |
3 |
Development of a Potent Inhibitor of the Plasmodium Proteasome with Reduced Mammalian Toxicity. |
University of California |
28236510 |
55 |
A strategy for dual inhibition of the proteasome and fatty acid synthase with belactosin C-orlistat hybrids. |
Baylor University |
21774748 |
30 |
Synthesis and structure-activity relationship of novel conformationally restricted analogues of serotonin as 5-HT6 receptor ligands. |
Suven Life Sciences |
2250662 |
140 |
Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. |
Glaxo Group Research |