The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26191366 |
66 |
Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. |
Indiana University School of Medicine |
25921264 |
21 |
Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy. |
Sanford-Burnham Medical Research Institute |
25003231 |
59 |
Therapeutic potential of targeting the oncogenic SHP2 phosphatase. |
Indiana University School of Medicine |
24997687 |
3 |
Inhibition of the lymphoid tyrosine phosphatase: the effect of zinc(II) ions and chelating ligand fragments on enzymatic activity. |
University of Utah |
25372368 |
58 |
Fast identification of novel lymphoid tyrosine phosphatase inhibitors using target-ligand interaction-based virtual screening. |
Shandong University |
23713581 |
75 |
A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases. |
Indiana University School of Medicine |
23499238 |
15 |
Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors. |
Chinese Academy of Medical Sciences and Peking Union Medical College |
23305444 |
171 |
Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold. |
Indiana University School of Medicine |
21341673 |
106 |
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells. |
University of Southern California |
22133902 |
9 |
Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors. |
Indiana University |
21116447 |
65 |
Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis. |
Indiana University School of Medicine |
18434147 |
35 |
Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase. |
Columbia University |
18056643 |
8 |
Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases. |
Indiana University School of Medicine |
21190368 |
60 |
Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids. |
Sanford-Burnham Medical Research Institute |
21129966 |
1 |
Oxidative inactivation of the lymphoid tyrosine phosphatase mediated by both general and active site directed NO donors. |
University of Utah |
20170098 |
21 |
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). |
Indiana University School of Medicine |
12951078 |
38 |
Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors. |
Abbott Laboratories |
28042046 |
12 |
Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity. |
Peking University |
25195011 |
24 |
A unique inhibitor binding site in ER K1/2 is associated with slow binding kinetics |
George Washington University |
17988101 |
7 |
Solution-phase parallel synthesis of carbamates as gamma-secretase inhibitors. |
Schering-Plough Research Institute |