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35 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26191366 66 Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors.EBI Indiana University School of Medicine
25921264 21 Perspective: Tyrosine phosphatases as novel targets for antiplatelet therapy.EBI Sanford-Burnham Medical Research Institute
25003231 59 Therapeutic potential of targeting the oncogenic SHP2 phosphatase.EBI Indiana University School of Medicine
24997687 3 Inhibition of the lymphoid tyrosine phosphatase: the effect of zinc(II) ions and chelating ligand fragments on enzymatic activity.EBI University of Utah
25372368 58 Fast identification of novel lymphoid tyrosine phosphatase inhibitors using target-ligand interaction-based virtual screening.EBI Shandong University
23713581 75 A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.EBI Indiana University School of Medicine
23499238 15 Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors.EBI Chinese Academy of Medical Sciences and Peking Union Medical College
23305444 171 Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.EBI Indiana University School of Medicine
21341673 106 Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.EBI University of Southern California
22133902 9 Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors.EBI Indiana University
21116447 65 Identification and characterization of novel inhibitors of mPTPB, an essential virulent phosphatase from Mycobacterium tuberculosis.EBI Indiana University School of Medicine
18434147 35 Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.EBI Columbia University
18056643 8 Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases.EBI Indiana University School of Medicine
21190368 60 Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.EBI Sanford-Burnham Medical Research Institute
21129966 1 Oxidative inactivation of the lymphoid tyrosine phosphatase mediated by both general and active site directed NO donors.EBI University of Utah
20170098 21 Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).EBI Indiana University School of Medicine
12951078 38 Discovery and SAR of novel, potent and selective protein tyrosine phosphatase 1B inhibitors.EBI Abbott Laboratories
28042046 12 Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity.BDB Peking University
25195011 24 A unique inhibitor binding site in ER K1/2 is associated with slow binding kineticsBDB George Washington University
17988101 7 Solution-phase parallel synthesis of carbamates as gamma-secretase inhibitors.BDB Schering-Plough Research Institute