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24 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
17353248 6 SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli.EBI Institut Pasteur Hellenique
17665896 30 4-Substituted trinems as broad spectrum beta-lactamase inhibitors: structure-based design, synthesis, and biological activity.EBI Lek Pharmaceuticals
13678405 23 A specific mechanism of nonspecific inhibition.EBI Northwestern University
8809160 132 Design, synthesis, and evaluation of 2 beta-alkenyl penam sulfone acids as inhibitors of beta-lactamases.EBI F. Hoffmann-La Roche
11959006 10 Design, synthesis and bioactivity evaluation of tribactam beta lactamase inhibitors.EBI Lek
 51 The synthesis and lactamase inhibitory activity of 6-(carboxymethylene)penicillins and 7-(carboxymethylene)cephalosporinsEBI TBA
 10 Synthesis and biological activity of novel penem sulfoxides and sulfonesEBI TBA
 22 Inhibition of the RTEM-1 β-lactamase by boronic acidsEBI TBA
17709463 4 TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases.EBI Chu Clermont-Ferrand
17956081 24 Optimizing cell permeation of an antibiotic resistance inhibitor for improved efficacy.EBI Università
16854068 59 Structure-activity relationship of 6-methylidene penems bearing 6,5 bicyclic heterocycles as broad-spectrum beta-lactamase inhibitors: evidence for 1,4-thiazepine intermediates with C7 R stereochemistry by computational methods.EBI Wyeth Research
15588091 25 Structure-activity relationship of 6-methylidene penems bearing tricyclic heterocycles as broad-spectrum beta-lactamase inhibitors: crystallographic structures show unexpected binding of 1,4-thiazepine intermediates.EBI Wyeth Research
15214794 20 Mechanism of inactivation of beta-lactamases by novel 6-methylidene penems elucidated using electrospray ionization mass spectrometry.EBI Wyeth Research
14980686 50 Penicillin-derived inhibitors that simultaneously target both metallo- and serine-beta-lactamases.EBI Southern Methodist University
11327608 45 Allyl and propargyl substituted penam sulfones as versatile intermediates toward the syntheses of new beta-lactamase inhibitors.EBI Wyeth-Ayerst Research
10890171 6 Synthesis and biological activities of an alpha-methyl and a beta-methyl carbapenem and the corresponding unsubstituted compound.EBI University Of Munich
10230627 14 6-(1-Hydroxyalkyl))penam sulfone derivatives as inhibitors of class A and class C beta-lactamases II.EBI Wyeth-Ayerst Research
10230626 22 6-(1-Hydroxyalkyl)penam sulfone derivatives as inhibitors of class A and class C beta-lactamases I.EBI Wyeth-Ayerst Research
7699694 66 Synthesis and biological activity of 7-alkylidenecephems.EBI Southern Methodist University
3257523 13 N-aryl 3-halogenated azetidin-2-ones and benzocarbacephems, inhibitors of beta-lactamases.EBI Cnrs-Cercoa
3039137 20 Synthesis and beta-lactamase inhibitory properties of 2 beta-[(1,2,3-triazol-1-yl)methyl]-2 alpha-methylpenam-3 alpha-carboxylic acid 1,1-dioxide and related triazolyl derivatives.EBI TBA