The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
24909677 |
19 |
Lead identification of benzimidazolone and azabenzimidazolone arylsulfonamides as CC-chemokine receptor 4 (CCR4) antagonists. |
Glaxosmithkline |
24090135 |
201 |
Design of substituted imidazolidinylpiperidinylbenzoic acids as chemokine receptor 5 antagonists: potent inhibitors of R5 HIV-1 replication. |
Sanofi |
23437772 |
35 |
Colloidal aggregation causes inhibition of G protein-coupled receptors. |
University of North Carolina At Chapel Hill |
20627722 |
89 |
Identification of a sulfonamide series of CCR2 antagonists. |
Glaxosmithkline |
22546204 |
9 |
Recent developments and biological activities of thiazolidinone derivatives: a review. |
Dr. Hari Singh Gour University |
23079519 |
86 |
In vivo activity of an azole series of CCR2 antagonists. |
Glaxosmithkline |
22931505 |
69 |
Chemokine receptor antagonists. |
National Heart and Lung Institute |
22437117 |
47 |
Lead optimisation of the N1 substituent of a novel series of indazole arylsulfonamides as CCR4 antagonists and identification of a candidate for clinical investigation. |
Glaxosmithkline |
22047688 |
51 |
CCR2 receptor antagonists: optimization of biaryl sulfonamides to increase activity in whole blood. |
Glaxosmithkline |
21341682 |
37 |
Discovery, optimization, and pharmacological characterization of novel heteroaroylphenylureas antagonists of C-C chemokine ligand 2 function. |
Telik |
20297846 |
33 |
Discovery of novel small molecule orally bioavailable C-X-C chemokine receptor 4 antagonists that are potent inhibitors of T-tropic (X4) HIV-1 replication. |
Genzyme |
19674898 |
31 |
Spiropiperidine CCR5 antagonists. |
Roche Palo Alto |
20099827 |
34 |
Discovery and optimization of novel 3-piperazinylcoumarin antagonist of chemokine-like factor 1 with oral antiasthma activity in mice. |
Chinese Academy of Medical Sciences and Peking Union Medical College |
19081254 |
33 |
Potent and orally bioavailable CCR4 antagonists: Synthesis and structure-activity relationship study of 2-aminoquinazolines. |
Astellas Pharma |
19014885 |
32 |
Discovery of a potent, selective and orally bioavailable 3,9-diazaspiro[5.5]undeca-2-one CCR5 antagonist. |
Roche Palo Alto |
18694645 |
25 |
Potent CCR4 antagonists: synthesis, evaluation, and docking study of 2,4-diaminoquinazolines. |
Astellas Pharma |
18539035 |
20 |
Discovery of potent CCR4 antagonists: Synthesis and structure-activity relationship study of 2,4-diaminoquinazolines. |
Astellas Pharma |
17395464 |
38 |
Small molecule antagonists of the CC chemokine receptor 4 (CCR4). |
Millennium Pharmaceuticals |
17098428 |
21 |
Core exploration in optimization of chemokine receptor CCR4 antagonists. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
16698264 |
37 |
Discovery of 3,5-bis(trifluoromethyl)benzyl L-arylglycinamide based potent CCR2 antagonists. |
Merck Research Laboratories |
16539392 |
29 |
Highly potent and orally active CCR5 antagonists as anti-HIV-1 agents: synthesis and biological activities of 1-benzazocine derivatives containing a sulfoxide moiety. |
Takeda Pharmaceutical |
16497499 |
36 |
Optimization of 2-aminothiazole derivatives as CCR4 antagonists. |
Amgen |
16236499 |
17 |
Optimization of CCR4 antagonists: side-chain exploration. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
15863339 |
29 |
Identification of chemokine receptor CCR4 antagonist. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
15026036 |
91 |
Discovery and SAR of trisubstituted thiazolidinones as CCR4 antagonists. |
Array Biopharma |
11720852 |
51 |
Design, synthesis, and SAR of heterocycle-containing antagonists of the human CCR5 receptor for the treatment of HIV-1 infection. |
Merck Research Laboratories |
11720851 |
52 |
Discovery of human CCR5 antagonists containing hydantoins for the treatment of HIV-1 infection. |
Merck Research Laboratories |
11311066 |
76 |
Design, synthesis, and discovery of a novel CCR1 antagonist. |
Banyu Tsukuba Research Institute In Collaboration With Merck Research Laboratories |
11206474 |
51 |
Antagonists of the human CCR5 receptor as anti-HIV-1 agents. Part 2: structure-activity relationships for substituted 2-Aryl-1-[N-(methyl)-N-(phenylsulfonyl)amino]-4-(piperidin-1-yl)butanes. |
Merck Research Laboratories |
10821717 |
29 |
Discovery of novel, potent, and selective small-molecule CCR5 antagonists as anti-HIV-1 agents: synthesis and biological evaluation of anilide derivatives with a quaternary ammonium moiety. |
Takeda Chemical Industries |