The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
23270988 |
4 |
Carbon-11 N-methyl alkylation of L-368,899 and in vivo PET imaging investigations for neural oxytocin receptors. |
Yerkes National Primate Research Center |
7629809 |
140 |
Amino acid side chain descriptors for quantitative structure-activity relationship studies of peptide analogues. |
University of Illinois At Chicago |
7752199 |
71 |
Effects of a D-Cys6/L-Cys6 interchange in nonselective and selective vasopressin and oxytocin antagonists. |
Medical College of Ohio |
17300166 |
88 |
Design and synthesis of the first selective agonists for the rat vasopressin V(1b) receptor: based on modifications of deamino-[Cys1]arginine vasopressin at positions 4 and 8. |
University of Montpellier |
16297621 |
17 |
Pyridobenzodiazepines: a novel class of orally active, vasopressin V2 receptor selective agonists. |
Wyeth Research |
16302826 |
129 |
Discovery and development of a new class of potent, selective, orally active oxytocin receptor antagonists. |
Serono Pharmaceutical Research Institute |
1331448 |
101 |
Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product. |
Merck Research Laboratories |
2167976 |
33 |
Receptor ligands which bind the oxytocin receptor with selectivity and high affinity. Chemical modification of a Streptomyces silvensis derived cyclic hexapeptide. |
Merck |
20550119 |
96 |
Oral oxytocin antagonists. |
Drugmoldesign |
| 66 |
Non-peptide oxytocin antagonists: identification and synthesis of a potent camphor aminosuccinimide |
TBA |
| 9 |
Potent, non-peptidic oxytocin receptor antagonists from a natural source |
TBA |
17316912 |
63 |
Synthesis and biological activity of oxytocin analogues containing conformationally-restricted residues in position 7. |
University of Patras |
11992787 |
37 |
Identification of potent and selective oxytocin antagonists. Part 2: further investigation of benzofuran derivatives. |
Glaxosmithkline |
10780900 |
5 |
A study of the relationship between biological activity and prolyl amide isomer geometry in oxytocin using 5-tert-butylproline to augment the Cys(6)-Pro(7) amide cis-isomer population. |
Université |
10340620 |
30 |
Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency. |
Merck Research Laboratories |
9873680 |
21 |
Nonpeptide oxytocin antagonists: potent, orally bioavailable analogs of L-371,257 containing a 1-R-(pyridyl)ethyl ether terminus. |
Merck Research Laboratories |
9622556 |
63 |
Development of orally active oxytocin antagonists: studies on 1-(1-[4-[1-(2-methyl-1-oxidopyridin-3-ylmethyl)piperidin-4-yloxy]-2- methoxybenzoyl]piperidin-4-yl)-1,4-dihydrobenz[d][1,3]oxazin-2-one (L-372,662) and related pyridines. |
Merck Research Laboratories |
9083475 |
4 |
Synthesis and pharmacology of novel analogues of oxytocin and deaminooxytocin: directed methods for the construction of disulfide and trisulfide bridges in peptides. |
University of Minnesota |
8258821 |
491 |
Nanomolar-affinity, non-peptide oxytocin receptor antagonists. |
Merck Research Laboratories |
8126695 |
35 |
1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo [2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperaz ine (L-368,899): an orally bioavailable, non-peptide oxytocin antagonist with potential utility for managing preterm labor. |
Merck Research Laboratories |
8021923 |
27 |
A new series of photoactivatable and iodinatable linear vasopressin antagonists. |
Upr 9023 Cnrs |
7473590 |
37 |
1-(1-[4-[(N-acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]piperidin-4- yl)-4H-3,1-benzoxazin-2(1H)-one (L-371,257): a new, orally bioavailable, non-peptide oxytocin antagonist. |
Merck Research Laboratories |
30199637 |
172 |
LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism. |
Umr7200 Cnrs/Universit£ |
2163451 |
45 |
Cyclic hexapeptide oxytocin antagonists. Potency-, selectivity-, and solubility-enhancing modifications. |
Merck Sharp & Dohme Research Laboratories |
1331449 |
268 |
Orally active, nonpeptide oxytocin antagonists. |
Merck Research Laboratories |