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34 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
25971770 10 Progress in discovery of small-molecule modulators of protein-protein interactions via fragment screening.EBI Pfizer
24266771 3 Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists.EBI Ruhr University of Bochum
23566315 3 Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.EBI The University of Arizona
21381769 56 Macrocycles are great cycles: applications, opportunities, and challenges of synthetic macrocycles in drug discovery.EBI Universite£
32276831 10 Chalcones bearing a 3,4,5-trimethoxyphenyl motif are capable of selectively inhibiting oncogenic K-Ras signaling.EBI Wright State University
32250617 27 Identification of the Clinical Development Candidate EBI Array Biopharma
32023060 19 Structure-Based Design and Pharmacokinetic Optimization of Covalent Allosteric Inhibitors of the Mutant GTPase KRASEBI Astrazeneca
30655937 10 Inhibitors of G12C Mutant Ras Proteins for the Treatment of Cancers.EBI Usona Institute
31706640 5 Selective apoptosis-inducing activity of synthetic hydrocarbon-stapled SOS1 helix with d-amino acids in H358 cancer cells expressing KRASEBI China Pharmaceutical University
31620220 11 Inhibitors of KRAS May Potentially Provide Effective Cancer Treatment.EBI Therachem Research Medilab
31531201 37 Discovery of EBI Amgen
31820981 62 Discovery of a Covalent Inhibitor of KRASEBI TBA
30613331 14 Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity.EBI Array Biopharma
30455147 7 Discovery of covalent enzyme inhibitors using virtual docking of covalent fragments.EBI University of Houston
28105276 19 Covalent Guanosine Mimetic Inhibitors of G12C KRAS.EBI Dana Farber Cancer Institute
26230724 10 New Frontiers in Druggability.EBI Stony Brook University
23585920 11 Inhibition of Ras-Effector Interaction by Cyclic Peptides.EBI The Ohio State University
30258528 1 Precedence and Promise of Covalent Inhibitors of EGFR and KRAS for Patients with Non-Small-Cell Lung Cancer.EBI Pfizer
28740607 6 Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d.EBI Takeda Pharmaceutical
28457754 17 Investigation of the structural requirements of K-Ras(G12D) selective inhibitory peptide KRpep-2d using alanine scans and cysteine bridging.EBI Takeda Pharmaceutical