The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28302506 |
28 |
Xanthine oxidase inhibitory activity of nicotino/isonicotinohydrazides: A systematic approach from in vitro, in silico to in vivo studies. |
University of Karachi |
28286211 |
37 |
Synthesis, screening and docking of fused pyrano[3,2-d]pyrimidine derivatives as xanthine oxidase inhibitor. |
Guru Nanak Dev University |
28131711 |
12 |
Discovery and biological evaluation of some (1H-1,2,3-triazol-4-yl)methoxybenzaldehyde derivatives containing an anthraquinone moiety as potent xanthine oxidase inhibitors. |
China Medical University |
27133595 |
12 |
Anti-gout nor-oleanane triterpenoids from the leaves of Stauntonia brachyanthera. |
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) |
26762836 |
16 |
Hydroxylated chalcones with dual properties: Xanthine oxidase inhibitors and radical scavengers. |
Northern Kentucky University |
26363870 |
32 |
Synthesis and evaluation of 1-hydroxy/methoxy-4-methyl-2-phenyl-1H-imidazole-5-carboxylic acid derivatives as non-purine xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
25113879 |
22 |
Synthesis and bioevaluation of 2-phenyl-4-methyl-1,3-selenazole-5-carboxylic acids as potent xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
2778 |
28 |
Synthesis and enzymic activity of some novel xanthine oxidase inhibitors. 3-Substituted 5,7-dihydroxypyrazolo(1,5-alpha)pyrimidines. |
TBA |
24508129 |
45 |
HTS followed by NMR based counterscreening. Discovery and optimization of pyrimidones as reversible and competitive inhibitors of xanthine oxidase. |
Astrazeneca |
24556143 |
5 |
Design, synthesis and molecular modeling of aloe-emodin derivatives as potent xanthine oxidase inhibitors. |
Hainan University |
24388807 |
12 |
Microwave assisted synthesis of naphthopyrans catalysed by silica supported fluoroboric acid as a new class of non purine xanthine oxidase inhibitors. |
Guru Nanak Dev University |
23265878 |
31 |
Lead optimization of isocytosine-derived xanthine oxidase inhibitors. |
Piramal Healthcare |
22901670 |
61 |
Synthesis, biological evaluation, and molecular docking of N-{3-[3-(9-methyl-9H-carbazol-3-yl)-acryloyl]-phenyl}-benzamide/amide derivatives as xanthine oxidase and tyrosinase inhibitors. |
Solapur University |
22483591 |
12 |
Identification of novel isocytosine derivatives as xanthine oxidase inhibitors from a set of virtual screening hits. |
Piramal Healthcare |
6547745 |
4 |
Isomeric N-methyl-7-deazaguanines: synthesis, structural assignment, and inhibitory activity on xanthine oxidase. |
TBA |
21862335 |
43 |
N-(1,3-Diaryl-3-oxopropyl)amides as a new template for xanthine oxidase inhibitors. |
Indo-Soviet Friendship College of Pharmacy |
21620698 |
8 |
Discovery of novel xanthone derivatives as xanthine oxidase inhibitors. |
Second Military Medical University |
21353569 |
54 |
A rational approach for the design and synthesis of 1-acetyl-3,5-diaryl-4,5-dihydro(1H)pyrazoles as a new class of potential non-purine xanthine oxidase inhibitors. |
Indo-Soviet Friendship College of Pharmacy |
21163661 |
26 |
Synthesis and xanthine oxidase inhibitory activity of 7-methyl-2-(phenoxymethyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-5-one derivatives. |
University of Mysore |
20189693 |
9 |
Synthesis of some 5-phenylisoxazole-3-carboxylic acid derivatives as potent xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
19783139 |
31 |
Discovery of 3-(2-cyano-4-pyridyl)-5-(4-pyridyl)-1,2,4-triazole, FYX-051 - a xanthine oxidoreductase inhibitor for the treatment of hyperuricemia [corrected] |
Fuji Yakuhin |
19388706 |
2 |
Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin. |
University of California |
3379415 |
15 |
Inhibition of Cow's Milk Xanthine Oxidase by Flavonoids |
TBA |
2723668 |
2 |
Pentagalloylglucose, A Xanthine Oxidase Inhibitor from a Paraguayan Crude Drug, "Molle-I" (Schinus terebinthifolius) |
TBA |
19027292 |
22 |
Design, synthesis, and pharmacological and pharmacokinetic evaluation of 3-phenyl-5-pyridyl-1,2,4-triazole derivatives as xanthine oxidoreductase inhibitors. |
Fuji Yakuhin |
17870212 |
7 |
Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. |
The University of Manchester |
11294382 |
13 |
Synthesis and structure-activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors. |
Welfide |
31557611 |
27 |
Design, synthesis and biological evaluation of N-(3-(1H-tetrazol-1-yl)phenyl)isonicotinamide derivatives as novel xanthine oxidase inhibitors. |
China Medical University |
31376568 |
28 |
Targeting the subpocket in xanthine oxidase: Design, synthesis, and biological evaluation of 2-[4-alkoxy-3-(1H-tetrazol-1-yl) phenyl]-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives. |
Shenyang Pharmaceutical University |
30885567 |
12 |
Design, synthesis and bioevaluation of 3-oxo-6-aryl-2,3-dihydropyridazine-4-carbohydrazide derivatives as novel xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
31369933 |
24 |
Design, synthesis and biological evaluation of 2-(4-alkoxy-3-cyano)phenyl-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid derivatives as novel xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
30719922 |
2 |
Propolis Components from Stingless Bees Collected on South Sulawesi, Indonesia, and Their Xanthine Oxidase Inhibitory Activity. |
University of Shizuoka |
30630716 |
5 |
Discovery of 2-phenylthiazole-4-carboxylic acid, a novel and potent scaffold as xanthine oxidase inhibitors. |
Guangzhou General Pharmaceutical Research Institute |
25060641 |
8 |
X-ray crystal structure of a xanthine oxidase complex with the flavonoid inhibitor quercetin. |
University of California |
29684895 |
28 |
Design, synthesis and biological evaluation of novel xanthine oxidase inhibitors bearing a 2-arylbenzo[b]furan scaffold. |
China Pharmaceutical University |
29207340 |
10 |
Xanthine oxidase inhibitory activity of natural and hemisynthetic flavonoids from Gardenia oudiepe (Rubiaceae) in vitro and molecular docking studies. |
Universidad Nacional De C£Rdoba |
29407989 |
38 |
Design, synthesis and biological evaluation of 1-hydroxy-2-phenyl-4-pyridyl-1H-imidazole derivatives as xanthine oxidase inhibitors. |
Shenyang Pharmaceutical University |
28918097 |
24 |
Synthesis and bioevaluation of 1-phenyl-pyrazole-4-carboxylic acid derivatives as potent xanthine oxidoreductase inhibitors. |
South China University of Technology |
29274704 |
13 |
Synthesis, structure-activity relationships, and mechanistic studies of 5-arylazo-tropolone derivatives as novel xanthine oxidase (XO) inhibitors. |
Tohoku Medical and Pharmaceutical University |
29032030 |
23 |
Design, synthesis and biological evaluation of N-(4-alkoxy-3-cyanophenyl)isonicotinamide/nicotinamide derivatives as novel xanthine oxidase inhibitors. |
China Medical University |
28693909 |
21 |
Synthesis and evaluation of 1-phenyl-1H-1,2,3-triazole-4-carboxylic acid derivatives as xanthine oxidase inhibitors. |
China Medical University |
28478180 |
69 |
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted pharmacokinetics and toxicity. |
University of Nis |
28655421 |
16 |
Synthesis and evaluation of hydroxychalcones as multifunctional non-purine xanthine oxidase inhibitors for the treatment of hyperuricemia. |
Guangxi Medical University |
28545814 |
19 |
Carboxylated aurone derivatives as potent inhibitors of xanthine oxidase. |
National Academy of Sciences of Ukraine |
21314246 |
16 |
Synthesis and biological evaluation of 2,5-disubstituted 1,3,4-oxadiazole derivatives with both COX and LOX inhibitory activity. |
Jamia Hamdard University |
22087650 |
9 |
Delineation of the Pasteurellaceae-specific GbpA-family of glutathione-binding proteins. |
Ghent University |