Affinity Data by PubMed id=17870212

PubMed code 17870212

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Thymidine phosphorylase (Homo sapiens (Human))	BDBM20079 (5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...) Show SMILES Clc1c(CN2CCCC2=N)[nH]c(=O)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant thymidine phosphorylase by [3H]thymidine incorporation assay				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50134399 (1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione \| 7...) Show SMILES O=c1[nH]c2[nH]ccc2c(=O)[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of bovine xanthine oxidase using hypoxanthine as a substrate				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50134399 (1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione \| 7...) Show SMILES O=c1[nH]c2[nH]ccc2c(=O)[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	7.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of bovine xanthine oxidase using xanthine as a substrate				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidine phosphorylase (Homo sapiens (Human))	BDBM50122764 (2-Amino-1-(5-bromo-2,6-dioxo-1,2,3,6-tetrahydro-py...) Show SMILES Nc1[nH+]ccn1Cc1[nH]c(=O)[nH]c(=O)c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant thymidine phosphorylase				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidine phosphorylase (Homo sapiens (Human))	BDBM20079 (5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...) Show SMILES Clc1c(CN2CCCC2=N)[nH]c(=O)[nH]c1=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant thymidine phosphorylase by [3H]thymidine incorporation assay				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Thymidine phosphorylase (Homo sapiens (Human))	BDBM50122770 (6-Amino-5-bromo-1H-pyrimidine-2,4-dione \| 6-Amino-...) Show SMILES Nc1[nH]c(=O)[nH]c(=O)c1Br Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant thymidine phosphorylase				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair
Thymidine phosphorylase (Homo sapiens (Human))	BDBM50134399 (1,7-Dihydro-pyrrolo[2,3-d]pyrimidine-2,4-dione \| 7...) Show SMILES O=c1[nH]c2[nH]ccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Manchester Curated by ChEMBL					Assay Description Inhibition of human recombinant thymidine phosphorylase				Eur J Med Chem 43: 1248-60 (2008) Article DOI: 10.1016/j.ejmech.2007.07.015 BindingDB Entry DOI: 10.7270/Q2Z31ZDP
The University of Manchester Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%