Affinity Data by PubMed id=11294382

PubMed code 11294382

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098068 (1-[3-CYANO-4-(NEOPENTYLOXY)PHENYL]-1H-PYRAZOLE-4-C...) Show SMILES CC(C)(C)COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098065 (1-(3-Cyano-4-isobutoxy-phenyl)-1H-pyrazole-4-carbo...) Show SMILES CC(C)COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098063 (1-(4-Butoxy-3-cyano-phenyl)-1H-pyrazole-4-carboxyl...) Show SMILES CCCCOc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098072 (1-(3-Cyano-4-octyloxy-phenyl)-1H-pyrazole-4-carbox...) Show SMILES CCCCCCCCOc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098062 (1-(4-Isobutoxy-3-nitro-phenyl)-1H-pyrazole-4-carbo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098071 (1-(3-Bromo-4-isobutoxy-phenyl)-1H-pyrazole-4-carbo...) Show SMILES CC(C)COc1ccc(cc1Br)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM35440 (ALLOPURINOL \| MLS000069453 \| SMR000059083 \| cid_20...) Show SMILES O=c1[nH]cnc2n[nH]cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098061 (1-(3-Cyano-4-methoxy-phenyl)-1H-pyrazole-4-carboxy...) Show SMILES COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098069 (1-[3-Cyano-4-(2-dimethylamino-ethoxy)-phenyl]-1H-p...) Show SMILES CN(C)CCOc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098067 (1-(4-Carboxymethoxy-3-cyano-phenyl)-1H-pyrazole-4-...) Show SMILES OC(=O)COc1ccc(cc1C#N)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098064 (1-(3-Cyano-phenyl)-1H-pyrazole-4-carboxylic acid \|...) Show SMILES OC(=O)c1cnn(c1)-c1cccc(c1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098066 (1-(3-Cyano-4-hydroxy-phenyl)-1H-pyrazole-4-carboxy...) Show SMILES OC(=O)c1cnn(c1)-c1ccc(O)c(c1)C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Xanthine dehydrogenase/oxidase (Bos taurus (Bovine))	BDBM50098070 (1-(4-Isobutoxy-phenyl)-1H-pyrazole-4-carboxylic ac...) Show SMILES CC(C)COc1ccc(cc1)-n1cc(cn1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Welfide Corporation Curated by ChEMBL					Assay Description In vitro inhibitory concentration against Xanthine oxidase				Bioorg Med Chem Lett 11: 879-82 (2001) BindingDB Entry DOI: 10.7270/Q2251HFC
Welfide Corporation Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%