BindingDB logo
myBDB logout

39 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
1995900 4 Romazarit: a potential disease-modifying antirheumatic drug.EBI Roche Products
2496230 1 Antiinflammatory activity of a series of substituted 2,3-dihydro-6-hydroxypyrimido[2,1-f]purine-4,8(1H,9H)-diones.EBI Schering-Plough
3086558 4 Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents.EBI TBA
6502598 1 Bulky amine analogues of ketoprofen: potent antiinflammatory agents.EBI TBA
7332706 24 2,3-Dihydrobenzofuran-2-ones: a new class of highly potent antiinflammatory agents.EBI TBA
6772786 3 Synthesis and antiinflammatory activity of some 2-(substituted-pyridinyl)benzimidazoles.EBI TBA
23266122 47 Novel benzoxazole inhibitors of mPGES-1.EBI Pfizer
1848292 116 Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.EBI Ici Pharmaceuticals Group
24900213 25 Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists.EBI TBA
1433181 39 Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors.EBI Warner-Lambert
1635053 47 5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.EBI Wyeth-Ayerst Research
2113951 134 1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity.EBI Pfizer
 8 Synthesis and biological evaluation of both enantiomers of L-761,000 as inhibitors of cyclooxygenase 1 and 2EBI TBA
 24 From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitorsEBI TBA
 11 Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di-t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazolesEBI TBA
 11 Synthesis and cyclooxygenase and 5-lipoxygenase inhibitory activity of some thiazolidene-4-one analogs of meclofenamic acidEBI TBA
 16 Synthesis of reversed hydroxamic acids of indomethacin: dual inhibitors of cyclooxygenase and 5-lipoxygenaseEBI TBA
 21 1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitorEBI TBA
 14 Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenaseEBI TBA
11591502 51 Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors.EBI RhôNe-Poulenc Rorer
10230624 110 N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase.EBI The R. W. Johnson Pharmaceutical Research Institute
28530811 13 Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases.EBI University of Pennsylvania
8515419 29 1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.EBI Warner-Lambert
30496988 25 Pharmaceutical and medicinal significance of sulfur (SEBI Wuhan University of Technology
10821716 31 Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase.EBI Shionogi
3806620 16 Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters.EBI TBA
3091830 41 Selective thromboxane synthetase inhibitors. 4. 2-(1H-imidazol-1-ylmethyl) carboxylic acids of benzo[b]furan, benzo[b]thiophene, indole, and naphthalene.EBI TBA
3090264 28 Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.EBI TBA
28835803 14 Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group.EBI University of Pennsylvania
2502629 90 Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis.EBI Rorer Central Research
2498516 4 N-[(arylmethoxy)phenyl] and N-[(arylmethoxy)naphthyl] sulfonamides: potent orally active leukotriene D4 antagonists of novel structure.EBI Wyeth-Ayerst Research
29031075 42 Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities.EBI Damanhour University
2213827 73 Penta- and hexadienoic acid derivatives: a novel series of 5-lipoxygenase inhibitors.EBI Centre De Recherches De Vitry
2115589 22 Antiinflammatory agents. 4. Syntheses and biological evaluation of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid.EBI A.H. Robins
2115586 29 Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase.EBI Warner-Lambert
2104935 10 N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure.EBI Wyeth-Ayerst Research
28757100 38 Design, synthesis and bioactivities of Celecoxib analogues or derivatives.EBI Chongqing Normal University
1847426 56 Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.EBI Warner-Lambert