The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
1995900 |
4 |
Romazarit: a potential disease-modifying antirheumatic drug. |
Roche Products |
2496230 |
1 |
Antiinflammatory activity of a series of substituted 2,3-dihydro-6-hydroxypyrimido[2,1-f]purine-4,8(1H,9H)-diones. |
Schering-Plough |
3086558 |
4 |
Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents. |
TBA |
6502598 |
1 |
Bulky amine analogues of ketoprofen: potent antiinflammatory agents. |
TBA |
7332706 |
24 |
2,3-Dihydrobenzofuran-2-ones: a new class of highly potent antiinflammatory agents. |
TBA |
6772786 |
3 |
Synthesis and antiinflammatory activity of some 2-(substituted-pyridinyl)benzimidazoles. |
TBA |
23266122 |
47 |
Novel benzoxazole inhibitors of mPGES-1. |
Pfizer |
1848292 |
116 |
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity. |
Ici Pharmaceuticals Group |
24900213 |
25 |
Novel 3-Oxazolidinedione-6-aryl-pyridinones as Potent, Selective, and Orally Active EP3 Receptor Antagonists. |
TBA |
1433181 |
39 |
Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors. |
Warner-Lambert |
1635053 |
47 |
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. |
Wyeth-Ayerst Research |
2113951 |
134 |
1,2-Dihydro-1-oxopyrrolo[3,2,1-kl]phenothiazine-2-carboxamides and congeners, dual cyclooxygenase/5-lipoxygenase inhibitors with antiinflammatory activity. |
Pfizer |
| 8 |
Synthesis and biological evaluation of both enantiomers of L-761,000 as inhibitors of cyclooxygenase 1 and 2 |
TBA |
| 24 |
From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors |
TBA |
| 11 |
Cyclooxygenase and 5-lipoxygenase inhibitory activity of 2,6 di-t-butylphenols linked by a sulfur atom to 1,3,4-thiadiazoles and 1,3,4-oxadiazoles |
TBA |
| 11 |
Synthesis and cyclooxygenase and 5-lipoxygenase inhibitory activity of some thiazolidene-4-one analogs of meclofenamic acid |
TBA |
| 16 |
Synthesis of reversed hydroxamic acids of indomethacin: dual inhibitors of cyclooxygenase and 5-lipoxygenase |
TBA |
| 21 |
1-Phenyl-[2H]-tetrahydropyridazin-3-one, A-53612, a selective orally active 5-lipoxygenase inhibitor |
TBA |
| 14 |
Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase |
TBA |
11591502 |
51 |
Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors. |
RhôNe-Poulenc Rorer |
10230624 |
110 |
N-hydroxyurea and hydroxamic acid inhibitors of cyclooxygenase and 5-lipoxygenase. |
The R. W. Johnson Pharmaceutical Research Institute |
28530811 |
13 |
Multitargeted Imidazoles: Potential Therapeutic Leads for Alzheimer's and Other Neurodegenerative Diseases. |
University of Pennsylvania |
8515419 |
29 |
1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities. |
Warner-Lambert |
30496988 |
25 |
Pharmaceutical and medicinal significance of sulfur (S |
Wuhan University of Technology |
10821716 |
31 |
Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase. |
Shionogi |
3806620 |
16 |
Leukotriene D4 antagonists and 5-lipoxygenase inhibitors. Synthesis of benzoheterocyclic [(methoxyphenyl)amino]oxoalkanoic acid esters. |
TBA |
3091830 |
41 |
Selective thromboxane synthetase inhibitors. 4. 2-(1H-imidazol-1-ylmethyl) carboxylic acids of benzo[b]furan, benzo[b]thiophene, indole, and naphthalene. |
TBA |
3090264 |
28 |
Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors. |
TBA |
28835803 |
14 |
Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group. |
University of Pennsylvania |
2502629 |
90 |
Differential effects of a series of hydroxamic acid derivatives on 5-lipoxygenase and cyclooxygenase from neutrophils and 12-lipoxygenase from platelets and their in vivo effects on inflammation and anaphylaxis. |
Rorer Central Research |
2498516 |
4 |
N-[(arylmethoxy)phenyl] and N-[(arylmethoxy)naphthyl] sulfonamides: potent orally active leukotriene D4 antagonists of novel structure. |
Wyeth-Ayerst Research |
29031075 |
42 |
Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities. |
Damanhour University |
2213827 |
73 |
Penta- and hexadienoic acid derivatives: a novel series of 5-lipoxygenase inhibitors. |
Centre De Recherches De Vitry |
2115589 |
22 |
Antiinflammatory agents. 4. Syntheses and biological evaluation of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid. |
A.H. Robins |
2115586 |
29 |
Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase. |
Warner-Lambert |
2104935 |
10 |
N-[(arylmethoxy)phenyl] carboxylic acids, hydroxamic acids, tetrazoles, and sulfonyl carboxamides. Potent orally active leukotriene D4 antagonists of novel structure. |
Wyeth-Ayerst Research |
28757100 |
38 |
Design, synthesis and bioactivities of Celecoxib analogues or derivatives. |
Chongqing Normal University |
1847426 |
56 |
Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors. |
Warner-Lambert |