The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 17125246 |
11 |
Discovery and development of 5-[(5S,9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl-methyl]-3-thiophenecarboxylic acid (BMS-587101)--a small molecule antagonist of leukocyte function associated antigen-1. |
Cerep |
| 24900456 |
46 |
Discovery and Development of Potent LFA-1/ICAM-1 Antagonist SAR 1118 as an Ophthalmic Solution for Treating Dry Eye. |
TBA |
| 12643901 |
42 |
N-Benzoyl amino acids as LFA-1/ICAM inhibitors 1: amino acid structure-activity relationship. |
Genentech |
| 20655213 |
31 |
Discovery of tetrahydroisoquinoline (THIQ) derivatives as potent and orally bioavailable LFA-1/ICAM-1 antagonists. |
Sunesis Pharmaceuticals |
| 15686945 |
19 |
1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1. |
Novartis Institutes For Biomedical Research |
| 15582439 |
84 |
Amino-substituted heterocycles as isosteres of trans-cinnamides: design and synthesis of heterocyclic biaryl sulfides as potent antagonists of LFA-1/ICAM-1 binding. |
Abbott Laboratories |
| 15109637 |
30 |
Statin-derived 1,3-oxazinan-2-ones as submicromolar inhibitors of LFA-1/ICAM-1 interaction: stabilization of the metabolically labile vanillyl side chain. |
Novartis Institutes For Biomedical Research |
| 15080978 |
66 |
N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: structure-activity relationship of the benzoyl moiety. |
Genentech |
| 12565959 |
9 |
1,4-Diazepane-2-ones as novel inhibitors of LFA-1. |
Novartis Institute For Biomedical Research |
| 11585452 |
291 |
Selective inhibition of ICAM-1 and E-selectin expression in human endothelial cells. 2. Aryl modifications of 4-(aryloxy)thieno[2,3-c]pyridines with fine-tuning at C-2 carbamides. |
Abbott Laboratories |
| 11520199 |
25 |
Discovery of potent antagonists of leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. 3. Amide (C-ring) structure-activity relationship and improvement of overall properties of arylthio cinnamides. |
Abbott Laboratories |
| 11327603 |
31 |
Discovery and SAR of diarylsulfide cyclopropylamide LFA-1/ICAM-1 interaction antagonists. |
Abbott Laboratories |
| 11300880 |
168 |
Discovery of inhibitors of cell adhesion molecule expression in human endothelial cells. 1. Selective inhibition of ICAM-1 and E-selectin expression. |
Abbott Laboratories |
| 11052808 |
75 |
Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead. |
Abbott Laboratories |
| 10853677 |
34 |
Discovery and evaluation of potent, tyrosine-based alpha4beta1 integrin antagonists. |
Celltech Chiroscience |
| 31082765 |
11 |
Structure-activity relationship and synthetic methodologies of ?-santonin derivatives with diverse bioactivities: A mini-review. |
Shanghai Ocean University |
| 10072689 |
39 |
Selective, tight-binding inhibitors of integrin alpha4beta1 that inhibit allergic airway responses. |
Biogen |
| 8145218 |
8 |
3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion. |
Warner-Lambert |
| 18672369 |
9 |
Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition. |
Korea Research Institute of Bioscience and Biotechnology |
| 11374943 |
2 |
Antimalarial, cytotoxic, and antifungal alkaloids from Duguetia hadrantha. |
University of Mississippi |
| 15165136 |
4 |
A new antimalarial quassinoid from Simaba orinocensis. |
University of Mississippi |
| 28734245 |
47 |
Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties. |
The Medical University of Silesia |
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