The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
28011205 |
3 |
Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation. |
Columbia University |
9873633 |
50 |
MEK inhibitors: the chemistry and biological activity of U0126, its analogs, and cyclization products. |
Dupont Pharmaceuticals |
15615512 |
21 |
Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
11934592 |
24 |
Photochemical preparation of a pyridone containing tetracycle: a Jak protein kinase inhibitor. |
Merck Research Laboratories |
11378364 |
34 |
Indazolylamino quinazolines and pyridopyrimidines as inhibitors of the EGFr and C-erbB-2. |
Research Biomet. Glaxo Wellcome Medicines Research Centre |
27329786 |
68 |
Discovery of 1-(1H-Pyrazolo[4,3-c]pyridin-6-yl)urea Inhibitors of Extracellular Signal-Regulated Kinase (ERK) for the Treatment of Cancers. |
Merck |
22119475 |
19 |
Fused thiophene derivatives as MEK inhibitors. |
Ucb Pharma |
17880056 |
52 |
4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase. |
University of Auckland |
29940463 |
46 |
Design and biological evaluation of novel triaryl pyrazoline derivatives with dioxane moiety for selective BRAF |
Nanjing University |
21985377 |
42 |
Synthesis and biological evaluation of novel N, N'-disubstituted urea and thiourea derivatives as potential anti-melanoma agents. |
Nanjing University |