The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
1433224 |
1 |
Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake. |
Warner-Lambert |
2544727 |
1 |
Sodium channel binding and anticonvulsant activities for the enantiomers of a bicyclic 2,4-oxazolidinedione and monocyclic models. |
University of Alabama |
2846842 |
14 |
Anticonvulsant activities of phenyl-substituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel. |
University of Alabama |
15177465 |
18 |
2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators. |
Institut Henri Beaufour |
10406642 |
8 |
Synthesis and preliminary biological evaluation of new alpha-amino amide anticonvulsants incorporating a dextromethorphan moiety. |
Pharmacia & Upjohn |
23121096 |
86 |
Ion channels as therapeutic targets: a drug discovery perspective. |
Pfizer |
10571163 |
14 |
A novel class of Na+ and Ca2+ channel dual blockers with highly potent anti-ischemic effects. |
Institute For Bio-Medical Research |
10498200 |
40 |
Sodium channel activity and sigma binding of 2-aminopropanamide anticonvulsants. |
Pharmacia & Upjohn |
| 15 |
Batrachotoxin binding site antagonists |
TBA |
21962108 |
14 |
Lactam-stabilized helical analogues of the analgesicµ-conotoxin KIIIA. |
Monash University |
17724025 |
8 |
Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. |
University of Utah |
15080972 |
64 |
The design, preparation and SAR of novel small molecule sodium (Na(+)) channel blockers. |
Arqule |
31117524 |
1 |
Isolation and Biological Activity of 8- Epitetrodotoxin and the Structure of a Possible Biosynthetic Shunt Product of Tetrodotoxin, Cep-226A, from the Newt Cynops ensicauda popei. |
Tohoku University |
12166948 |
77 |
Synthesis and structure-activity relationships of 6,7-benzomorphan derivatives as use-dependent sodium channel blockers for the treatment of stroke. |
Boehringer Ingelheim Pharma |
10229624 |
25 |
Comparative molecular field analysis of hydantoin binding to the neuronal voltage-dependent sodium channel. |
University of Alabama At Birmingham |
10411478 |
5 |
Anticonvulsant and sodium channel-blocking properties of novel 10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide derivatives. |
Bial |
9046351 |
13 |
Effects of log P and phenyl ring conformation on the binding of 5-phenylhydantoins to the voltage-dependent sodium channel. |
University of Alabama At Birmingham |
7562939 |
7 |
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations. |
Howard University |
7932556 |
11 |
Bicyclic hydantoins with a bridgehead nitrogen. Comparison of anticonvulsant activities with binding to the neuronal voltage-dependent sodium channel. |
University of Alabama At Birmingham |