Affinity Data by PubMed id=10229624

PubMed code 10229624

Found 25 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472563 (CHEMBL417155) Show SMILES CCCCCCCC1(NC(=O)NC1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472561 (CHEMBL39043) Show SMILES CCCCCCCCCC1(NC(=O)NC1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472564 (CHEMBL287713) Show SMILES CCCCCCCC(O)(C(N)=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472565 (CHEMBL289499) Show SMILES CCCCCCC1(NC(=O)NC1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470016 (CHEMBL288505) Show SMILES CCCCCC1(NC(=O)NC1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50101816 (CHEBI:8107 \| Dilabid \| Dilantin \| Dilantin-125 \| D...) Show SMILES OC1=NC(=O)C(N1)(c1ccccc1)c1ccccc1 \|t:1\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472562 (CHEMBL39326) Show SMILES O=C1NC(=O)C(N1)(C1CCCCC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471519 (CHEMBL39889) Show SMILES CCCCC1(NC(=O)NC1=O)c1cccc(C)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471517 (CHEMBL39247) Show SMILES CCCCC1(NC(=O)NC1=O)c1ccc(C)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470014 (CHEMBL39010) Show SMILES CCCCC1(NC(=O)NC1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50003659 (5H-dibenzo[b,f]azepine-5-carboxamide \| CARBAMAZEPI...) Show SMILES NC(=O)N1c2ccccc2C=Cc2ccccc12 \|c:11\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470011 (CHEMBL288861) Show SMILES CCCC1(NC(=O)NC1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471514 (CHEMBL38760) Show SMILES CCCCC1(NC(=O)NC1=O)c1ccccc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471514 (CHEMBL38760) Show SMILES CCCCC1(NC(=O)NC1=O)c1ccccc1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471518 (CHEMBL290743) Show SMILES CC12N(CCc3ccccc13)C(=O)NC2=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471515 (CHEMBL290090) Show SMILES O=C1NC(=O)C2(CCCCCc3ccccc23)N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50022495 (6,7,8,9-tetrahydro-2'H,5'H-spiro[benzo[7]annulene-...) Show SMILES O=C1NC(=O)C2(CCCCc3ccccc23)N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470013 (CHEMBL39810) Show SMILES CCCCC1(NC(=O)N(C)C1=O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.85E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470015 (CHEMBL39126) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470015 (CHEMBL39126) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.27E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470012 (CHEMBL38675) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50470012 (CHEMBL38675) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50471516 (CHEMBL38588) Show SMILES CCN1C(=O)NC(=O)C1(C)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50022454 (3',4'-dihydro-2'H-spiro[imidazolidine-4,1'-naphtha...) Show SMILES O=C1NC(=O)C2(CCCc3ccccc23)N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.51E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50022457 (2',3'-dihydro-2H,5H-spiro[imidazolidine-4,1'-inden...) Show SMILES O=C1NC(=O)C2(CCc3ccccc23)N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.11E+6	n/a	n/a	n/a	n/a	n/a	n/a
University of Alabama at Birmingham Curated by ChEMBL					Assay Description In vitro inhibition of Voltage-gated sodium channel by the displacement of [3H]batrachotoxin A 20-alpha-benzoate in rat brain cerebral cortex synapto...				J Med Chem 42: 1537-45 (1999) Article DOI: 10.1021/jm980556l BindingDB Entry DOI: 10.7270/Q2RJ4N61
University of Alabama at Birmingham Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%