Affinity Data by PubMed id=10411478

PubMed code 10411478

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472303 (CHEMBL314266) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.13E+5	n/a	n/a	n/a	n/a	n/a	n/a
BIAL Curated by ChEMBL					Assay Description Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes				J Med Chem 42: 2582-7 (1999) Article DOI: 10.1021/jm980627g BindingDB Entry DOI: 10.7270/Q2QN69GZ
BIAL Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50240669 (Acetic acid (S)-5-carbamoyl-10,11-dihydro-5H-diben...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	<1.38E+5	n/a	n/a	n/a	n/a	n/a	n/a
BIAL Curated by ChEMBL					Assay Description Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes				J Med Chem 42: 2582-7 (1999) Article DOI: 10.1021/jm980627g BindingDB Entry DOI: 10.7270/Q2QN69GZ
BIAL Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50472302 (CHEMBL315644) Show SMILES CC(=O)OC1Cc2ccccc2N(C(N)=O)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.41E+5	n/a	n/a	n/a	n/a	n/a	n/a
BIAL Curated by ChEMBL					Assay Description Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes				J Med Chem 42: 2582-7 (1999) Article DOI: 10.1021/jm980627g BindingDB Entry DOI: 10.7270/Q2QN69GZ
BIAL Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM34179 (CHEMBL1068 \| MLS000084586 \| OXCARBAZEPINE \| SMR000...) Show SMILES NC(=O)N1c2ccccc2CC(=O)c2ccccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	<1.61E+5	n/a	n/a	n/a	n/a	n/a	n/a
BIAL Curated by ChEMBL					Assay Description Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes				J Med Chem 42: 2582-7 (1999) Article DOI: 10.1021/jm980627g BindingDB Entry DOI: 10.7270/Q2QN69GZ
BIAL Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus)	BDBM50003659 (5H-dibenzo[b,f]azepine-5-carboxamide \| CARBAMAZEPI...) Show SMILES NC(=O)N1c2ccccc2C=Cc2ccccc12 \|c:11\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
BIAL Curated by ChEMBL					Assay Description Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomes				J Med Chem 42: 2582-7 (1999) Article DOI: 10.1021/jm980627g BindingDB Entry DOI: 10.7270/Q2QN69GZ
BIAL Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%