The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
15026065 |
8 |
A prodrug approach to COX-2 inhibitors with methylsulfone. |
Amorepacific |
11206450 |
36 |
2,2-Dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors. |
Pacific Corporation R & D Center |
26774035 |
16 |
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity. |
University of Siena |
24629448 |
2 |
Synthetic approaches to the 2012 new drugs. |
Pharmaphase |
23534442 |
32 |
Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors. |
Universit£ |
23131542 |
16 |
Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme. |
Sapienza University of Rome |
11101350 |
72 |
1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole derivatives: a new series of potent and selective COX-2 inhibitors in which a sulfonyl group is not a structural requisite. |
Institut De Recherche Servier |
1635053 |
47 |
5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors. |
Wyeth-Ayerst Research |
15109651 |
54 |
Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities. |
Yeungnam University |
21992176 |
52 |
Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties. |
Sapienza University of Rome |
22172309 |
12 |
Novel bioactive metabolites of dipyrone (metamizol). |
Philipps-Universit£T |
20056549 |
12 |
Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production. |
National Taiwan University |
19957931 |
66 |
Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation. |
Sapienza University of Rome |
19286379 |
8 |
Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib. |
Chinese Academy of Medical Sciences |
18752957 |
44 |
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents. |
Sapienza University of Rome |
18598017 |
28 |
Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity. |
Universita Di Siena |
17915854 |
38 |
Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity. |
Sapienza University of Rome |
15857149 |
24 |
1,5-Diarylpyrrole-3-acetic acids and esters as novel classes of potent and highly selective cyclooxygenase-2 inhibitors. |
Sapienza University of Rome |
31427145 |
16 |
Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold. |
Universit£ |
30396033 |
33 |
Medicinal chemistry of vicinal diaryl scaffold: A mini review. |
The M.S University of Baroda |
24373735 |
48 |
Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors. |
Universit£ |
23680444 |
36 |
A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity. |
Universit£ |
14761182 |
118 |
In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives. |
Amorepacific R&D Center |