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23 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
15026065 8 A prodrug approach to COX-2 inhibitors with methylsulfone.EBI Amorepacific
11206450 36 2,2-Dimethyl-4,5-diaryl-3(2H)furanone derivatives as selective cyclo-oxygenase-2 inhibitors.EBI Pacific Corporation R & D Center
26774035 16 Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity.EBI University of Siena
24629448 2 Synthetic approaches to the 2012 new drugs.EBI Pharmaphase
23534442 32 Novel analgesic/anti-inflammatory agents: 1,5-diarylpyrrole nitrooxyalkyl ethers and related compounds as cyclooxygenase-2 inhibiting nitric oxide donors.EBI Universit£
23131542 16 Improving the solubility of a new class of antiinflammatory pharmacodynamic hybrids, that release nitric oxide and inhibit cycloxygenase-2 isoenzyme.EBI Sapienza University of Rome
11101350 72 1,3-Diaryl-4,5,6,7-tetrahydro-2H-isoindole derivatives: a new series of potent and selective COX-2 inhibitors in which a sulfonyl group is not a structural requisite.EBI Institut De Recherche Servier
1635053 47 5-lipoxygenase: properties, pharmacology, and the quinolinyl(bridged)aryl class of inhibitors.EBI Wyeth-Ayerst Research
15109651 54 Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities.EBI Yeungnam University
21992176 52 Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties.EBI Sapienza University of Rome
22172309 12 Novel bioactive metabolites of dipyrone (metamizol).EBI Philipps-Universit£T
20056549 12 Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production.EBI National Taiwan University
19957931 66 Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation.EBI Sapienza University of Rome
19286379 8 Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib.EBI Chinese Academy of Medical Sciences
18752957 44 Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents.EBI Sapienza University of Rome
18598017 28 Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity.EBI Universita Di Siena
17915854 38 Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity.EBI Sapienza University of Rome
15857149 24 1,5-Diarylpyrrole-3-acetic acids and esters as novel classes of potent and highly selective cyclooxygenase-2 inhibitors.EBI Sapienza University of Rome
31427145 16 Synthesis, biological evaluation and molecular modeling of novel selective COX-2 inhibitors: sulfide, sulfoxide, and sulfone derivatives of 1,5-diarylpyrrol-3-substituted scaffold.EBI Universit£
30396033 33 Medicinal chemistry of vicinal diaryl scaffold: A mini review.EBI The M.S University of Baroda
24373735 48 Enhancing the pharmacodynamic profile of a class of selective COX-2 inhibiting nitric oxide donors.EBI Universit£
23680444 36 A class of pyrrole derivatives endowed with analgesic/anti-inflammatory activity.EBI Universit£
14761182 118 In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives.EBI Amorepacific R&D Center