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16 articles for thisTarget


The following articles (labelled with PubMed ID or TBD) are for your review
PMIDDataArticle TitleOrganization
26619267 29 3-Oxo-hexahydro-1H-isoindole-4-carboxylic Acid as a Drug Chiral Bicyclic Scaffold: Structure-Based Design and Preparation of Conformationally Constrained Covalent and Noncovalent Prolyl Oligopeptidase Inhibitors.EBI Mcgill University
24763264 7 Synthesis and biological evaluation of novel (123)I-labeled 4-(4-iodophenyl)butanoyl-L-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo.EBI University of Helsinki
23121075 119 P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy.EBI University of Antwerp
20058865 59 Inhibitors of prolyl oligopeptidases for the therapy of human diseases: defining diseases and inhibitors.EBI Mcgill University
18053726 364 Inhibitors of proteases and amide hydrolases that employ an alpha-ketoheterocycle as a key enabling functionality.EBI Johnson & Johnson Pharmaceutical Research & Development
16033257 52 Dicarboxylic acid azacycle l-prolyl-pyrrolidine amides as prolyl oligopeptidase inhibitors and three-dimensional quantitative structure-activity relationship of the enzyme-inhibitor interactions.EBI University of Kuopio
10821712 18 Quantized surface complementarity diversity (QSCD): a model based on small molecule-target complementarity.EBI Neogenesis
 34 Peptidyl -keto thiazole as potent thrombin inhibitorsEBI TBA
 6 α-Ketothiazole inhibitors of prolyl endopeptidaseEBI TBA
16279765 3 Synthesis and characterization of the novel fluorescent prolyl oligopeptidase inhibitor 4-fluoresceinthiocarbamoyl-6-aminocaproyl-L-prolyl-2(S)-(hydroxyacetyl)pyrrolidine.EBI University of Kuopio
15509157 14 A cyclopent-2-enecarbonyl group mimics proline at the P2 position of prolyl oligopeptidase inhibitors.EBI University of Kuopio
14521416 29 New prolyl oligopeptidase inhibitors developed from dicarboxylic acid bis(l-prolyl-pyrrolidine) amides.EBI University of Kuopio
12238937 13 Dicarboxylic acid bis(L-prolyl-pyrrolidine) amides as prolyl oligopeptidase inhibitors.EBI University of Kuopio
31857839 28 Tetrazole as a Replacement of the Electrophilic Group in Characteristic Prolyl Oligopeptidase Inhibitors.EBI University of Helsinki
7932578 20 Synthesis and structure-activity relationships of peptidyl alpha-keto heterocycles as novel inhibitors of prolyl endopeptidase.EBI Meiji Seika Kaisha