8 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
25754491	11	8-(3-chloro-4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one derivatives as potent and selective phosphodiesterase 5 inhibitors.	Mitsubishi Tanabe Pharma
25455484	26	The discovery of avanafil for the treatment of erectile dysfunction: a novel pyrimidine-5-carboxamide derivative as a potent and highly selective phosphodiesterase 5 inhibitor.	Mitsubishi Tanabe Pharma
25442307	17	Design and synthesis of novel 5-(3,4,5-trimethoxybenzoyl)-4-aminopyrimidine derivatives as potent and selective phosphodiesterase 5 inhibitors: scaffold hopping using a pseudo-ring by intramolecular hydrogen bond formation.	Mitsubishi Tanabe Pharma
11405657	123	Novel, potent, and selective phosphodiesterase 5 inhibitors: synthesis and biological activities of a series of 4-aryl-1-isoquinolinone derivatives.	Tanabe Seiyaku
12824030	67	1,7- and 2,7-naphthyridine derivatives as potent and highly specific PDE5 inhibitors.	Tanabe Seiyaku
10197972	133	1-Arylnaphthalene lignan: a novel scaffold for type 5 phosphodiesterase inhibitor.	Tanabe Seiyaku
25062128	16	Discovery of clinical candidate 1-(4-(3-(4-(1H-benzo[d]imidazole-2-carbonyl)phenoxy)pyrazin-2-yl)piperidin-1-yl)ethanone (AMG 579), a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A).	Amgen
24400806	101	Novel class of benzoic acid ester derivatives as potent PDE4 inhibitors for inhaled administration in the treatment of respiratory diseases.	Chiesi Farmaceutici