The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26411795 |
40 |
Discovery of spirocyclic-diamine inhibitors of mammalian acetyl CoA-carboxylase. |
Pfizer |
25333641 |
11 |
Recent advances in the development of acetyl-CoA carboxylase (ACC) inhibitors for the treatment of metabolic disease. |
Amgen |
25423286 |
26 |
Decreasing the rate of metabolic ketone reduction in the discovery of a clinical acetyl-CoA carboxylase inhibitor for the treatment of diabetes. |
Pfizer |
22677317 |
23 |
Symmetrical approach of spiro-pyrazolidinediones as acetyl-CoA carboxylase inhibitors. |
Takeda Pharmaceutical |
16789734 |
42 |
Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors. |
Abbott Laboratories |
22148323 |
53 |
Maximizing lipophilic efficiency: the use of Free-Wilson analysis in the design of inhibitors of acetyl-CoA carboxylase. |
Pfizer |
21515056 |
61 |
Design of small molecule inhibitors of acetyl-CoA carboxylase 1 and 2 showing reduction of hepatic malonyl-CoA levels in vivo in obese Zucker rats. |
Astrazeneca Research and Development |
21082864 |
87 |
Identification and synthesis of novel inhibitors of acetyl-CoA carboxylase with in vitro and in vivo efficacy on fat oxidation. |
Sanofi-Aventis Deutschland |
20219367 |
96 |
Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. |
Pfizer |
19853443 |
6 |
(4-Piperidinyl)-piperazine: a new platform for acetyl-CoA carboxylase inhibitors. |
Taisho Pharmaceutical |
19097787 |
2 |
Synthesis of spiro[chroman-2,4'-piperidin]-4-one derivatives as acetyl-CoA carboxylase inhibitors. |
Torrent Pharmaceuticals |
12951100 |
6 |
Cyclohexanedione herbicides are inhibitors of rat heart acetyl-CoA carboxylase. |
Eli Lilly |