The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
20558059 |
19 |
Structure-activity relationships and hepatic safety risks of thiazole agonists of the thrombopoietin receptor. |
Pfizer |
18778936 |
37 |
Discovery and biological evaluation of benzo[a]carbazole-based small molecule agonists of the thrombopoietin (Tpo) receptor. |
Genomics Institute of The Novartis Research Foundation |
18396041 |
44 |
Molecular features crucial to the activity of pyrimidine benzamide-based thrombopoietin receptor agonists. |
Pfizer |
20800483 |
9 |
Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists. |
Shanghai Hengrui Pharmaceuticals |
20675136 |
5 |
Synthesis and biological evaluation of oxoindolin-3-ylidene ethyl benzothiohydrazides as non-peptide TPO mimics. |
Shanghai Hengrui Pharmaceuticals |
19186055 |
20 |
The identification of orally bioavailable thrombopoietin agonists. |
Pfizer |
18783949 |
22 |
Optimization of small molecule agonists of the thrombopoietin (Tpo) receptor derived from a benzo[a]carbazole hit scaffold. |
Genomics Institute of The Novartis Research Foundation |
17707640 |
116 |
Pyrimidine benzamide-based thrombopoietin receptor agonists. |
Pfizer |
16376078 |
10 |
New benzimidazoles as thrombopoietin receptor agonists. |
Glaxosmithkline |
11606138 |
45 |
Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis. |
Glaxosmithkline |