Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179471 (5-[1-[2-(4'-tert-Butyl-2-hydroxy-biphenyl-3-yl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179475 (5-((2-(5-(4-tert-butylphenyl)furan-2-yl)-1H-benzo[...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 720 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179477 (5-[1-[2-(4'-tert-Butyl-biphenyl-3-yl)-1H-benzoimid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179472 (5-((2-(4-(3,4-dimethylphenyl)thiophen-2-yl)-1H-ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 780 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179476 (5-((2-(5-(3,4-dimethylphenyl)thiophen-2-yl)-1H-ben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.75E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179473 (2-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179470 (5-((2-(6-(3,4-dichlorophenyl)pyridin-2-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179474 (3-(2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benzo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | n/a | 4.50E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179478 (5-((2-(6-(3,4-dimethylphenyl)pyridin-2-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thrombopoietin receptor (Homo sapiens (Human)) | BDBM50179469 (5-((2-(6-(4-tert-butylphenyl)pyridin-2-yl)-1H-benz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL | Assay Description Agonist activity as induced proliferation in Ba/F3-hTpoR murine lymphocyte expressing human TPOR | Bioorg Med Chem Lett 16: 1212-6 (2006) Article DOI: 10.1016/j.bmcl.2005.11.096 BindingDB Entry DOI: 10.7270/Q2V124BM | |||||||||||
More data for this Ligand-Target Pair |