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SMILES: CCNCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1

InChI Key: InChIKey=LZBRXQYXNRYEEU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384673   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene Wnt-1


(Homo sapiens (human))		BDBM384673
PNG
(US10285982, Compound 90)
Show SMILES CCNCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1
Show InChI InChI=1S/C26H22N8/c1-2-27-11-16-8-18(14-29-12-16)22-10-21-24(15-31-22)33-34-25(21)23-9-20-19(5-7-30-26(20)32-23)17-4-3-6-28-13-17/h3-10,12-15,27H,2,11H2,1H3,(H,30,32)(H,33,34)
UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 3.20E+3n/an/an/an/a



Istanbul University



Assay Description
Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...

Bioorg Med Chem 16: 9113-20 (2008)


BindingDB Entry DOI: 10.7270/Q2J105G8
More data for this
Ligand-Target Pair