Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene Wnt-1' and Ligand = 'BDBM384673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene Wnt-1 (Homo sapiens (human))	BDBM384673 (US10285982, Compound 90) Show SMILES CCNCc1cncc(c1)-c1cc2c(n[nH]c2cn1)-c1cc2c(ccnc2[nH]1)-c1cccnc1 Show InChI InChI=1S/C26H22N8/c1-2-27-11-16-8-18(14-29-12-16)22-10-21-24(15-31-22)33-34-25(21)23-9-20-19(5-7-30-26(20)32-23)17-4-3-6-28-13-17/h3-10,12-15,27H,2,11H2,1H3,(H,30,32)(H,33,34)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Istanbul University					Assay Description Reporter cell lines can be generated by stably transducing cancer cell lines (e.g., colon cancer) or primary cells (e.g., IEC-6 intestinal cells) wit...				Bioorg Med Chem 16: 9113-20 (2008) BindingDB Entry DOI: 10.7270/Q2J105G8
					More data for this Ligand-Target Pair