BDBM50329429 5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-3-yl)-1Hpyrrole-3-carboxamide::CHEMBL1270619::US9670191, G13
SMILES: Cn1cc(-c2[nH]c(cc2C(N)=O)-c2ccnc(N)n2)c2ccccc12
InChI Key: InChIKey=NYNANQKQYVAHFV-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM50329429 (5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | US Patent | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
NERVIANO MEDICAL SCIENCES S.R.L. US Patent | Assay Description The assay consists of the transfer of radioactivity labeled phosphate moiety by the kinase to an acceptor substrate. The resulting 33P-labeled produc... | US Patent US9670191 (2017) BindingDB Entry DOI: 10.7270/Q2X63K3K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase (Homo sapiens (Human)) | BDBM50329429 (5-(2-Amino-pyrimidin-4-yl)-2-(1-methyl-1H-indol-3-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl Curated by ChEMBL | Assay Description Inhibition of Cdc7 | J Med Chem 53: 7296-315 (2010) Article DOI: 10.1021/jm100504d BindingDB Entry DOI: 10.7270/Q24T6JM3 | |||||||||||
More data for this Ligand-Target Pair |