Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27427 (8-methyl-11-thia-9,14,16-triazatetracyclo[8.7.0.0^...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 0.5 | -55.2 | 5 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27428 (12-ethyl-11,13-dimethyl-8-thia-3,5,10-triazatricyc...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1 | -53.4 | 10 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27429 (9-methyl-17-thia-2,12,14-triazatetracyclo[8.7.0.0^...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2 | -51.6 | 20 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27430 (11,13-dimethyl-12-(prop-2-en-1-yl)-8-thia-3,5,10-t...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2 | -51.6 | 20 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27431 (7-methyl-10-thia-8,13,15-triazatetracyclo[7.7.0.0^...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3 | -50.6 | 30 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27432 (11,12,13-trimethyl-8-thia-3,5,10-triazatricyclo[7....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 4 | -49.9 | 40 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27433 (16-methyl-8-thia-3,5,10-triazatetracyclo[7.7.0.0^{...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5 | -49.3 | 50 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27434 (11,13-dimethyl-8-thia-3,5,10-triazatricyclo[7.4.0....) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 40 | -43.9 | 400 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27435 (12-benzyl-11,13-dimethyl-8-thia-3,5,10-triazatricy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 200 | -39.8 | 2.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27436 (11-cyclopropyl-13-(trifluoromethyl)-8-thia-3,5,10-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 400 | -38.0 | 4.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27437 (12-phenyl-8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 900 | -35.9 | 9.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27438 (ethyl 6-amino-11-methyl-8-thia-3,5,10-triazatricyc...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.00E+3 | -35.6 | 1.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27439 (8-thia-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 1.20E+3 | -35.2 | 1.20E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27440 (N,11,13-trimethyl-8-thia-3,5,10-triazatricyclo[7.4...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | >-32.8 | >3.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27441 (N,N,11,13-tetramethyl-8-thia-3,5,10-triazatricyclo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | >-32.8 | >3.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27442 (11,13-dimethyl-N-phenyl-8-thia-3,5,10-triazatricyc...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | >3.00E+3 | >-32.8 | >3.00E+4 | n/a | n/a | n/a | n/a | 7.5 | 37 |
Roche | Assay Description The assay was carried out in the reaction buffer containing Cdc7/Dbf4, His6-MCM2, and ATP/[gamma-33P]ATP in the presence of test compounds. After inc... | Bioorg Med Chem Lett 19: 319-23 (2009) Article DOI: 10.1016/j.bmcl.2008.11.093 BindingDB Entry DOI: 10.7270/Q20G3HG2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27359 (7-ethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27380 ((7S)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27391 (5,13,17-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27371 (2-(2-aminopyrimidin-4-yl)-7,7-dimethyl-1H,4H,5H,6H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27362 (7-(2-fluoroethyl)-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27370 (2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1H,4H,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27348 (6-(2-methylpropyl)-2-(pyridin-4-yl)-1H,4H,5H,6H,7H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27361 (7-cyclobutyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27413 (2-(2-aminopyrimidin-4-yl)-1-(2-fluoroethyl)-1H,4H,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27363 (7,7-dimethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrro...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27390 (2-(2-amino-5-bromopyrimidin-4-yl)-1H,4H,5H,6H,7H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27368 (2-(2-aminopyrimidin-4-yl)-7-(propan-2-yl)-1H,4H,5H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27377 (2-(2-aminopyrimidin-4-yl)-7-(2-hydroxyethyl)-1H,4H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27412 (2-(2-aminopyrimidin-4-yl)-1-(cyclopropylmethyl)-1H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27406 (2-(2-aminopyrimidin-4-yl)-1-(2,2,2-trifluoroethyl)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27372 (2-(2-aminopyrimidin-4-yl)-7,7-diethyl-1H,4H,5H,6H,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27347 (6-cyclopropyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27367 (2-(2-aminopyrimidin-4-yl)-7-ethyl-1H,4H,5H,6H,7H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27379 ((7R)-2-(2-aminopyrimidin-4-yl)-7-(2-fluoroethyl)-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27369 (2-(2-aminopyrimidin-4-yl)-7-cyclobutyl-1H,4H,5H,6H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27364 (7,7-diethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrol...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27346 (6-(propan-2-yl)-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27366 (2-(2-aminopyrimidin-4-yl)-7-methyl-1H,4H,5H,6H,7H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27375 (2-(2-aminopyrimidin-4-yl)-7-[2-(benzyloxy)ethyl]-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27351 (2-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27421 (2-[2-(phenylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27351 (2-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27404 (2-(2-aminopyrimidin-4-yl)-1-ethyl-1H,4H,5H,6H,7H-p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27355 (2-(2-aminopyrimidin-4-yl)-6-(2-methylpropyl)-1H,4H...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27382 (2-(3-fluoropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27344 (2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27374 (2-(2-aminopyrimidin-4-yl)-7-(3,3,3-trifluoropropyl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27358 (7-methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 52: 293-307 (2009) Article DOI: 10.1021/jm800977q BindingDB Entry DOI: 10.7270/Q27W69JX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A (Homo sapiens (Human)) | BDBM27344 (2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.9 | 25 |
Nerviano Medical Sciences Srl | Assay Description The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ... | J Med Chem 51: 487-501 (2008) Article DOI: 10.1021/jm700956r BindingDB Entry DOI: 10.7270/Q247485B | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |
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