BDBM87263 2-amino-1-(3,5-dichlorophenyl)-1',7,7-trimethyl-2',5-dioxo-1,1',3',4,5,6,7,8-octahydrospiro[quinoline-4,3'-(2'H)-indole]-3-carbonitrile::2-amino-1-(3,5-dichlorophenyl)-1',7,7-trimethyl-2',5-dioxo-3-spiro[6,8-dihydroquinoline-4,3'-indole]carbonitrile::2-amino-1-(3,5-dichlorophenyl)-1',7,7-trimethyl-2',5-dioxospiro[6,8-dihydroquinoline-4,3'-indole]-3-carbonitrile::2-amino-1-(3,5-dichlorophenyl)-2',5-diketo-1',7,7-trimethyl-spiro[6,8-dihydroquinoline-4,3'-indoline]-3-carbonitrile::2-azanyl-1-[3,5-bis(chloranyl)phenyl]-1',7,7-trimethyl-2',5-bis(oxidanylidene)spiro[6,8-dihydroquinoline-4,3'-indole]-3-carbonitrile::MLS000545135::SMR000161610::cid_5075681

SMILES: CN1C(=O)C2(C(C#N)C(=N)N(C3=C2C(=O)CC(C)(C)C3)c2cc(Cl)cc(Cl)c2)c2ccccc12

InChI Key: InChIKey=UJJDJVYSFUHJKP-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 87263   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha trans-inducing protein (VP16) (Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)	BDBM87263 (2-amino-1-(3,5-dichlorophenyl)-1',7,7-trimethy...) Show SMILES CN1C(=O)C2(C(C#N)C(=N)N(C3=C2C(=O)CC(C)(C)C3)c2cc(Cl)cc(Cl)c2)c2ccccc12 |c:11| Show InChI InChI=1S/C26H22Cl2N4O2/c1-25(2)11-20-22(21(33)12-25)26(17-6-4-5-7-19(17)31(3)24(26)34)18(13-29)23(30)32(20)16-9-14(27)8-15(28)10-16/h4-10,18,30H,11-12H2,1-3H3	MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2D21W6V
					More data for this Ligand-Target Pair
nuclear receptor coactivator 3 isoform a (Homo sapiens (Human))	BDBM87263 (2-amino-1-(3,5-dichlorophenyl)-1',7,7-trimethy...) Show SMILES CN1C(=O)C2(C(C#N)C(=N)N(C3=C2C(=O)CC(C)(C)C3)c2cc(Cl)cc(Cl)c2)c2ccccc12 |c:11| Show InChI InChI=1S/C26H22Cl2N4O2/c1-25(2)11-20-22(21(33)12-25)26(17-6-4-5-7-19(17)31(3)24(26)34)18(13-29)23(30)32(20)16-9-14(27)8-15(28)10-16/h4-10,18,30H,11-12H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q2HT2MXV
					More data for this Ligand-Target Pair
Nuclear receptor coactivator 1 (Homo sapiens (Human))	BDBM87263 (2-amino-1-(3,5-dichlorophenyl)-1',7,7-trimethy...) Show SMILES CN1C(=O)C2(C(C#N)C(=N)N(C3=C2C(=O)CC(C)(C)C3)c2cc(Cl)cc(Cl)c2)c2ccccc12 |c:11| Show InChI InChI=1S/C26H22Cl2N4O2/c1-25(2)11-20-22(21(33)12-25)26(17-6-4-5-7-19(17)31(3)24(26)34)18(13-29)23(30)32(20)16-9-14(27)8-15(28)10-16/h4-10,18,30H,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>3.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2012) BindingDB Entry DOI: 10.7270/Q28914F2
					More data for this Ligand-Target Pair