BDBM106559 US8586600, II-54

SMILES: CC(Cl)C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1

InChI Key: InChIKey=WKTBMWCHAMDMIB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 106559   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM106559 (US8586600, II-54) Show SMILES CC(Cl)C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C26H23ClN6O2/c1-16-5-8-21(31-25(35)18-6-9-20(10-7-18)30-24(34)17(2)27)14-23(16)33-26-29-13-11-22(32-26)19-4-3-12-28-15-19/h3-15,17H,1-2H3,(H,30,34)(H,31,35)(H,29,32,33)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Avilomics Research, Inc. US Patent					Assay Description Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...				US Patent US8586600 (2013) BindingDB Entry DOI: 10.7270/Q2M61HWH
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM106559 (US8586600, II-54) Show SMILES CC(Cl)C(=O)Nc1ccc(cc1)C(=O)Nc1ccc(C)c(Nc2nccc(n2)-c2cccnc2)c1 Show InChI InChI=1S/C26H23ClN6O2/c1-16-5-8-21(31-25(35)18-6-9-20(10-7-18)30-24(34)17(2)27)14-23(16)33-26-29-13-11-22(32-26)19-4-3-12-28-15-19/h3-15,17H,1-2H3,(H,30,34)(H,31,35)(H,29,32,33)	PDB KEGG DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Avilomics Research, Inc. US Patent					Assay Description Compounds may also be assayed as inhibitors of PDGFR in a manner substantially similar to the method described in Roberts, et al., “Antiangiogen...				US Patent US8586600 (2013) BindingDB Entry DOI: 10.7270/Q2M61HWH
					More data for this Ligand-Target Pair