BDBM107110 US8592425, 14

SMILES: N[C@H]1CCCC(F)(F)C1NC(=O)c1cc(cs1)-c1cnc2cccnn12

InChI Key: InChIKey=VQUYUSDGYQLMQE-VPHXOMNUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107110   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MAP/microtubule affinity-regulating kinase 3 (Homo sapiens (Human))	BDBM107110 (US8592425, 14) Show SMILES N[C@H]1CCCC(F)(F)C1NC(=O)c1cc(cs1)-c1cnc2cccnn12 |r| Show InChI InChI=1S/C17H17F2N5OS/c18-17(19)5-1-3-11(20)15(17)23-16(25)13-7-10(9-26-13)12-8-21-14-4-2-6-22-24(12)14/h2,4,6-9,11,15H,1,3,5,20H2,(H,23,25)/t11-,15?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description MARK3 activity was assayed in vitro using a Cdc25C biotinylated peptide substrate (Cell Signalling Technologies). The phosphopeptide product was quan...				US Patent US8592425 (2013) BindingDB Entry DOI: 10.7270/Q28P5Z48
					More data for this Ligand-Target Pair