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SMILES: Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1cnc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccno1

InChI Key: InChIKey=QNVIMPQAFIYICG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107207 (US8592426, 57) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1cnc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccno1 Show InChI InChI=1S/C24H20ClFN8O3/c1-34-32-21(31-33-34)19-15(9-14(25)10-16(19)26)13-8-12-2-3-17(20(12)27-11-13)29-23(36)24(5-6-24)30-22(35)18-4-7-28-37-18/h4,7-11,17H,2-3,5-6H2,1H3,(H,29,36)(H,30,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107207 (US8592426, 57) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1cnc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)c1ccno1 Show InChI InChI=1S/C24H20ClFN8O3/c1-34-32-21(31-33-34)19-15(9-14(25)10-16(19)26)13-8-12-2-3-17(20(12)27-11-13)29-23(36)24(5-6-24)30-22(35)18-4-7-28-37-18/h4,7-11,17H,2-3,5-6H2,1H3,(H,29,36)(H,30,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair