BDBM11913 (1S,3S,5S)-2-[(2S)-piperidin-2-ylcarbonyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile::substituted diprolyl nitrile 6

SMILES: O=C([C@@H]1CCCCN1)N1[C@H]2C[C@H]2C[C@H]1C#N

InChI Key: InChIKey=MEIRVURVJOLSIQ-RCWTZXSCSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11913   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase IV (Sus scrofa (pig))	BDBM11913 ((1S,3S,5S)-2-[(2S)-piperidin-2-ylcarbonyl]-2-azabi...) Show SMILES O=C([C@@H]1CCCCN1)N1[C@H]2C[C@H]2C[C@H]1C#N |r| Show InChI InChI=1S/C12H17N3O/c13-7-9-5-8-6-11(8)15(9)12(16)10-3-1-2-4-14-10/h8-11,14H,1-6H2/t8-,9+,10+,11+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	>-6.75	n/a	n/a	n/a	n/a	n/a	7.4	22
Bristol-Myers Squibb Pharmaceutical Research Institute					Assay Description Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...				Bioorg Med Chem Lett 15: 3992-5 (2005) Article DOI: 10.1016/j.bmcl.2005.06.043 BindingDB Entry DOI: 10.7270/Q2CN7259
					More data for this Ligand-Target Pair