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SMILES: CCn1ccc2cnc(NC(=O)c3ccc(c(C)c3)[C@@](C)(O)CO)cc12

InChI Key: InChIKey=QJLUVUWHGZTKRP-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128411   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase kinase kinase 5


(Homo sapiens (Human))		BDBM128411
PNG
(US8802695, 27)
Show SMILES CCn1ccc2cnc(NC(=O)c3ccc(c(C)c3)[C@@](C)(O)CO)cc12 |r|
Show InChI InChI=1S/C20H23N3O3/c1-4-23-8-7-15-11-21-18(10-17(15)23)22-19(25)14-5-6-16(13(2)9-14)20(3,26)12-24/h5-11,24,26H,4,12H2,1-3H3,(H,21,22,25)/t20-/m0/s1
PDB

KEGG

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Similars
US Patent
n/an/a 528n/an/an/an/a7.325



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...

US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair