Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 5' and Ligand = 'BDBM128411'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM128411 (US8802695, 27) Show SMILES CCn1ccc2cnc(NC(=O)c3ccc(c(C)c3)[C@@](C)(O)CO)cc12 |r| Show InChI InChI=1S/C20H23N3O3/c1-4-23-8-7-15-11-21-18(10-17(15)23)22-19(25)14-5-6-16(13(2)9-14)20(3,26)12-24/h5-11,24,26H,4,12H2,1-3H3,(H,21,22,25)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	528	n/a	n/a	n/a	n/a	7.3	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...				US Patent US8802695 (2014) BindingDB Entry DOI: 10.7270/Q27W69WD
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