BDBM130376 N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-(cyclohexylmethyl)pyridine-2- carboxamide (2)
SMILES: O=C(Nc1ccc(cc1Cc1ccccc1)-c1nnn[nH]1)c1cccc(CC2CCCCC2)n1
InChI Key: InChIKey=DXIJKKFLXBIMCT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Protein UL24 homolog (Human herpesvirus 8) | BDBM130376 (N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-...) | MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
University of California at San Francisco | Assay Description Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ... | Biochemistry 53: 4648-60 (2014) Article DOI: 10.1021/bi5003234 BindingDB Entry DOI: 10.7270/Q2WH2NQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epstein-Barr nuclear antigen 1 (Human herpesvirus 4) | BDBM130376 (N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
University of California at San Francisco | Assay Description Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ... | Biochemistry 53: 4648-60 (2014) Article DOI: 10.1021/bi5003234 BindingDB Entry DOI: 10.7270/Q2WH2NQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Capsid scaffolding protein (Human cytomegalovirus (strain AD169) (HHV-5) (Huma...) | BDBM130376 (N-[2-Benzyl-4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]-6-...) | PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
University of California at San Francisco | Assay Description Compounds were prepared in 100% DMSO from 10 to 0.156 mM and/or from 5 to 0.078 mM. The P6 substrate concentrations were 5, 65, and 150 µM for KSHV, ... | Biochemistry 53: 4648-60 (2014) Article DOI: 10.1021/bi5003234 BindingDB Entry DOI: 10.7270/Q2WH2NQW | |||||||||||
More data for this Ligand-Target Pair |