BDBM130379 N-hydroxy-L-arginine (NOHA)
SMILES: NC(=N)NCCC[C@H](NO)C(O)=O
InChI Key: InChIKey=WQFIAVZQVYASHZ-BYPYZUCNSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase (SmARG) (Schistosoma mansoni (flatworms)) | BDBM130379 (N-hydroxy-L-arginine (NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description Briefly, 0.5-50 mM L-arginine (pH 8.5) was added to a solution of 50 mM 4-(2-hydroxyethyl)piperazine-1-propanesulfonic acid (EPPS) (pH 8.5) and 100 &... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (SmARG) (Schistosoma mansoni (flatworms)) | BDBM130379 (N-hydroxy-L-arginine (NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase (SmARG) (Schistosoma mansoni (flatworms)) | BDBM130379 (N-hydroxy-L-arginine (NOHA)) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 330 | n/a | n/a | n/a | 8.5 | n/a |
University of Pennsylvania | Assay Description SmARG was dialyzed against 50 mM bicine (pH 8.5), 100 μM MnCl2, and 1.0 mM TCEP [5% (v/v) DMSO was included in the dialysis buffer when SmARG wa... | Biochemistry 53: 4671-4684 (2014) Article DOI: 10.1021/bi5004519 BindingDB Entry DOI: 10.7270/Q2RR1WZQ | |||||||||||
More data for this Ligand-Target Pair |