BDBM136303 US8853224, 3.4

SMILES: OC[C@H](O)CN(Cc1c[nH]c2c1nc[nH]c2=O)Cc1ccccc1

InChI Key: InChIKey=WBNKKFGASWUKMH-CQSZACIVSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136303   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Plasmodium falciparum)	BDBM136303 (US8853224, 3.4) Show SMILES OC[C@H](O)CN(Cc1c[nH]c2c1nc[nH]c2=O)Cc1ccccc1 Show InChI InChI=1S/C17H20N4O3/c22-10-14(23)9-21(7-12-4-2-1-3-5-12)8-13-6-18-16-15(13)19-11-20-17(16)24/h1-6,11,14,18,22-23H,7-10H2,(H,19,20,24)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	25
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent					Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...				US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM136303 (US8853224, 3.4) Show SMILES OC[C@H](O)CN(Cc1c[nH]c2c1nc[nH]c2=O)Cc1ccccc1 Show InChI InChI=1S/C17H20N4O3/c22-10-14(23)9-21(7-12-4-2-1-3-5-12)8-13-6-18-16-15(13)19-11-20-17(16)24/h1-6,11,14,18,22-23H,7-10H2,(H,19,20,24)/t14-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	25
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent					Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...				US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84
					More data for this Ligand-Target Pair