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SMILES: CN1C(=O)Cc2ccc(cc12)-c1cnc(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1

InChI Key: InChIKey=STMRZFZITLOXOD-DAGLJCOKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138126   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 1


(Homo sapiens (Human))		BDBM138126
PNG
(US8871783, 12)
Show SMILES CN1C(=O)Cc2ccc(cc12)-c1cnc(CC(NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1 |r|
Show InChI InChI=1S/C22H23N5O2S/c1-27-17-7-13(3-2-12(17)8-20(27)28)18-11-24-19(30-18)9-16(10-23)26-22(29)21-14-4-5-15(6-14)25-21/h2-3,7,11,14-16,21,25H,4-6,8-9H2,1H3,(H,26,29)/t14-,15+,16?,21-/m0/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 14.9 -10.7n/an/an/an/an/a6.025



Boehringer Ingelheim International GmBh

US Patent


Assay Description
The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,...

US Patent US8871783 (2014)


BindingDB Entry DOI: 10.7270/Q2F18XF1
More data for this
Ligand-Target Pair