null
SMILES: CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)s1
InChI Key: InChIKey=KTVUUDSQXGTMCQ-VKDGWMQASA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 1 (Homo sapiens (Human)) | BDBM138137 (US8871783, 23) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.90 | -11.6 | n/a | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmBh US Patent | Assay Description The following buffers were used: MES buffer: 25 mM MES, 50 mM NaCl, 5 mM DTT, adjusted to pH 6.0, containing 0.1% BSA; TAGZyme Buffer: 20 mM NaH2PO4,... | US Patent US8871783 (2014) BindingDB Entry DOI: 10.7270/Q2F18XF1 | |||||||||||
More data for this Ligand-Target Pair |