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SMILES: CS(=O)(=O)c1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)[C@@]23C[C@H](CN2)CCC3)C#N)cc1

InChI Key: InChIKey=FDUAQHDMKJKRLP-WSUBETFTSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139517   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 1


(Homo sapiens (Human))		BDBM139517
PNG
(US8889708, 16)
Show SMILES CS(=O)(=O)c1cc(ccc1C#N)-c1ccc(C[C@H](NC(=O)[C@@]23C[C@H](CN2)CCC3)C#N)cc1 |r|
Show InChI InChI=1S/C25H26N4O3S/c1-33(31,32)23-12-20(8-9-21(23)14-26)19-6-4-17(5-7-19)11-22(15-27)29-24(30)25-10-2-3-18(13-25)16-28-25/h4-9,12,18,22,28H,2-3,10-11,13,16H2,1H3,(H,29,30)/t18-,22+,25-/m1/s1
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PC cid
PC sid
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Similars
US Patent
n/an/a 1.22E+3n/an/an/an/an/a25



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...

US Patent US8889708 (2014)


BindingDB Entry DOI: 10.7270/Q2JM28BB
More data for this
Ligand-Target Pair