null

SMILES: COc1cc(ccc1OC(C)C)-c1cc(O[C@H](C)[C@H]2CNC(=O)C2)c2cccnc2c1

InChI Key: InChIKey=ZZGANYRCHFYCMC-VQIMIIECSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 140284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM140284 (US8912173, 10) Show SMILES COc1cc(ccc1OC(C)C)-c1cc(O[C@H](C)[C@H]2CNC(=O)C2)c2cccnc2c1 |r| Show InChI InChI=1S/C25H28N2O4/c1-15(2)30-22-8-7-17(11-24(22)29-4)18-10-21-20(6-5-9-26-21)23(12-18)31-16(3)19-13-25(28)27-14-19/h5-12,15-16,19H,13-14H2,1-4H3,(H,27,28)/t16-,19-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	7.5	-80
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US8912173 (2014) BindingDB Entry DOI: 10.7270/Q2TX3D3T
					More data for this Ligand-Target Pair