BDBM141006 US8916576, 211

SMILES: CCCC(=O)Oc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1

InChI Key: InChIKey=WZWBQRCMIMNTNG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141006   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM141006 (US8916576, 211) Show SMILES CCCC(=O)Oc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1 Show InChI InChI=1S/C25H21N5O2/c1-2-6-23(31)32-19-8-5-7-16(14-19)24-28-22-10-4-3-9-20(22)25(29-24)27-18-11-12-21-17(13-18)15-26-30-21/h3-5,7-15H,2,6H2,1H3,(H,26,30)(H,27,28,29)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Surface Logix, Inc. US Patent					Assay Description ROCK-II inhibitory activity can be measured using the ROCK-II Assay Kit (Molecular Devices, inc.; Sunnyvale, Calif.).				US Patent US8916576 (2014) BindingDB Entry DOI: 10.7270/Q2P55M6K
					More data for this Ligand-Target Pair