null
SMILES: COCCCn1cc(CN(C2CC2)C(=O)[C@H]2CNCCO2)c2ccccc12
InChI Key: InChIKey=OHELVELDNLQVJI-HXUWFJFHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Renin (Homo sapiens (Human)) | BDBM149462 (US8975252, 39) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | 37 |
Shanghai Pharmaceuticals Holding Co., Ltd.; Mitsubishi Tanabe Pharma Corporation US Patent | Assay Description A renin substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluoro... | US Patent US8975252 (2015) BindingDB Entry DOI: 10.7270/Q2TB15NG | |||||||||||
More data for this Ligand-Target Pair |