BDBM152480 Z-L-Am7(AcEtMe)-QA (2)

SMILES: COCCOCC(=O)SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12

InChI Key: InChIKey=ADSFNXXUDGBABJ-VWLOTQADSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 152480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM152480 (Z-L-Am7(AcEtMe)-QA (2)) Show SMILES COCCOCC(=O)SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C29H35N3O6S/c1-36-17-18-37-21-26(33)39-19-7-3-6-14-25(32-29(35)38-20-22-10-4-2-5-11-22)28(34)31-24-15-8-12-23-13-9-16-30-27(23)24/h2,4-5,8-13,15-16,25H,3,6-7,14,17-21H2,1H3,(H,31,34)(H,32,35)/t25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu Institute of Technology					Assay Description For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...				Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2
					More data for this Ligand-Target Pair
Histone deacetylase 6 (HDAC6) (Mus musculus)	BDBM152480 (Z-L-Am7(AcEtMe)-QA (2)) Show SMILES COCCOCC(=O)SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C29H35N3O6S/c1-36-17-18-37-21-26(33)39-19-7-3-6-14-25(32-29(35)38-20-22-10-4-2-5-11-22)28(34)31-24-15-8-12-23-13-9-16-30-27(23)24/h2,4-5,8-13,15-16,25H,3,6-7,14,17-21H2,1H3,(H,31,34)(H,32,35)/t25-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu Institute of Technology					Assay Description For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...				Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM152480 (Z-L-Am7(AcEtMe)-QA (2)) Show SMILES COCCOCC(=O)SCCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1cccc2cccnc12 |r| Show InChI InChI=1S/C29H35N3O6S/c1-36-17-18-37-21-26(33)39-19-7-3-6-14-25(32-29(35)38-20-22-10-4-2-5-11-22)28(34)31-24-15-8-12-23-13-9-16-30-27(23)24/h2,4-5,8-13,15-16,25H,3,6-7,14,17-21H2,1H3,(H,31,34)(H,32,35)/t25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu Institute of Technology					Assay Description For the enzyme assay, 10 µL of the enzyme fraction was added to 1 µL of fluorescent substrate (2 mM Ac-KGLGK(Ac)-MCA) and 9 µL of histone deacetylase...				Bioorg Chem 59: 145-50 (2015) Article DOI: 10.1016/j.bioorg.2015.02.009 BindingDB Entry DOI: 10.7270/Q2T152C2
					More data for this Ligand-Target Pair